FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W77084620> ?p ?o ?g. }

• W77084620 endingPage "5769" @default.
• W77084620 startingPage "5769" @default.
• W77084620 abstract "Abstract Introduction: In addition to breast and colorectal cancers, multiple myeloma has also been associated with vitamin D deficiency. Given the role of vitamin D in calcium absorption and bone metabolism, it is crucial to maintain sufficient levels for multiple myeloma patients because of their high risk of bone-related complications. We hypothesized that there was a high prevalence of vitamin D deficiency and insufficiency among multiple myeloma patients. We also hypothesized that there is inadequate screening of vitamin D levels throughout community oncology clinics nationwide. Methods: This study both evaluated multiple myeloma patients from a single medical practice specializing in this B-cell malignancy who had a 25-OH vitamin D level determined, and separately determined the proportion of oncology sites that screen for this vitamin among their patients. Charts were reviewed from the medical practice specializing in multiple myeloma, and only the first vitamin D determination was analyzed in the study. Demographics and the presence of the following complications at the time or within 1 year from when vitamin D levels were assessed: peripheral neuropathy, skeletal-related events and bone disease. We defined skeletal-related events as pathological fractures, spinal cord compression or requirement for radiation or surgery, and bone disease as having one of the following: osteoporosis, osteopenia or lytic bone disease. Patients were categorized as either having sufficient (> 30 ng/ml), insufficient (20 to < 30 ng/ml) or deficient (<20 ng/ml) 25-OH vitamin D levels. Chi square analysis was used to compare the proportion of patients with specific complications to their 25-OH vitamin D levels. To determine the rate of vitamin D screening among community oncologists, Site Information Forms from 508 sites throughout the United States were reviewed which asked these groups whether they screen patients for vitamin D levels. Results: One hundred sixty-nine multiple myeloma patients were enrolled in the study. Their median age was 67, the mean was 65.4 (range, 38-85) and the gender breakdown was 62% male and 38% female. 25-OH vitamin D levels were sufficient in less than two-thirds (64%) of patients with 22% and 14% of patents showing insufficient and deficient levels of this vitamin, respectively. The proportions of patients with specific complications in relationship to their vitamin D levels are shown below.Abstract 5769. Table 1ComplicationVitamin D deficientVitamin D insufficientVitamin D deficientPeripheral neuropathy65%65%59%Bone disease85%82%87%Skeletal-related events70%62%58% Chi square analysis showed no significant differences in complications rates as related to vitamin D levels although skeletal-related events were more frequently observed among patients with vitamin D levels below the normal range (insufficient or deficient). Of the 508 sites that were asked on the Site Information Forms to provide information on whether their physicians assess vitamin D levels as part of their standard of care of their patients, 97% responded that they did not assess vitamin D levels as part of their standard of care of these patients. Conclusion: Vitamin D levels are frequently low among multiple myeloma patients and, despite this, screening levels of this vitamin is not thought to be part of the routine work up by the vast majority of oncologists in the United States. Disclosures No relevant conflicts of interest to declare." @default.
• W77084620 created "2016-06-24" @default.
• W77084620 creator A5017627000 @default.
• W77084620 creator A5019989988 @default.
• W77084620 creator A5040835019 @default.
• W77084620 creator A5044039905 @default.
• W77084620 creator A5074171315 @default.
• W77084620 date "2014-12-06" @default.
• W77084620 modified "2023-10-01" @default.
• W77084620 title "Vitamin D Levels Are Frequently below Normal in Multiple Myeloma Patients and Are Infrequently Assessed By Their Treating Physicians" @default.
• W77084620 doi "https://doi.org/10.1182/blood.v124.21.5769.5769" @default.
• W77084620 hasPublicationYear "2014" @default.
• W77084620 type Work @default.
• W77084620 sameAs 77084620 @default.
• W77084620 citedByCount "5" @default.
• W77084620 countsByYear W770846202018 @default.
• W77084620 countsByYear W770846202019 @default.
• W77084620 countsByYear W770846202020 @default.
• W77084620 countsByYear W770846202023 @default.
• W77084620 crossrefType "journal-article" @default.
• W77084620 hasAuthorship W77084620A5017627000 @default.
• W77084620 hasAuthorship W77084620A5019989988 @default.
• W77084620 hasAuthorship W77084620A5040835019 @default.
• W77084620 hasAuthorship W77084620A5044039905 @default.
• W77084620 hasAuthorship W77084620A5074171315 @default.
• W77084620 hasConcept C124490489 @default.
• W77084620 hasConcept C126322002 @default.
• W77084620 hasConcept C141071460 @default.
• W77084620 hasConcept C2776169692 @default.
• W77084620 hasConcept C2776364478 @default.
• W77084620 hasConcept C2776541429 @default.
• W77084620 hasConcept C2776886416 @default.
• W77084620 hasConcept C2777083390 @default.
• W77084620 hasConcept C2778049618 @default.
• W77084620 hasConcept C2779740938 @default.
• W77084620 hasConcept C71924100 @default.
• W77084620 hasConcept C90924648 @default.
• W77084620 hasConceptScore W77084620C124490489 @default.
• W77084620 hasConceptScore W77084620C126322002 @default.
• W77084620 hasConceptScore W77084620C141071460 @default.
• W77084620 hasConceptScore W77084620C2776169692 @default.
• W77084620 hasConceptScore W77084620C2776364478 @default.
• W77084620 hasConceptScore W77084620C2776541429 @default.
• W77084620 hasConceptScore W77084620C2776886416 @default.
• W77084620 hasConceptScore W77084620C2777083390 @default.
• W77084620 hasConceptScore W77084620C2778049618 @default.
• W77084620 hasConceptScore W77084620C2779740938 @default.
• W77084620 hasConceptScore W77084620C71924100 @default.
• W77084620 hasConceptScore W77084620C90924648 @default.
• W77084620 hasIssue "21" @default.
• W77084620 hasLocation W770846201 @default.
• W77084620 hasOpenAccess W77084620 @default.
• W77084620 hasPrimaryLocation W770846201 @default.
• W77084620 hasRelatedWork W1819605542 @default.
• W77084620 hasRelatedWork W1977698049 @default.
• W77084620 hasRelatedWork W1994490491 @default.
• W77084620 hasRelatedWork W2012921467 @default.
• W77084620 hasRelatedWork W2098696139 @default.
• W77084620 hasRelatedWork W2144480179 @default.
• W77084620 hasRelatedWork W2350254144 @default.
• W77084620 hasRelatedWork W2527802633 @default.
• W77084620 hasRelatedWork W2570861097 @default.
• W77084620 hasRelatedWork W2937062120 @default.
• W77084620 hasVolume "124" @default.
• W77084620 isParatext "false" @default.
• W77084620 isRetracted "false" @default.
• W77084620 magId "77084620" @default.
• W77084620 workType "article" @default.