Matches in SemOpenAlex for { <https://semopenalex.org/work/W771337024> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W771337024 abstract "Glutathione-S-transferase (GST) family enzymes are implicated in the pathophysiology of bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD). In some cases both illnesses exhibit similar pathomorphologic and clinical features, indicating common genetic basis of predisposing to development of disease. To assess genetic susceptibility we conducted association analysis of glutathione-S-transferases Мu (M), Theta (Т) and Pi (Р) gene polymorphism with disease development in 85 adult asthma, 60 COPD subjects and 64 control subjects. Present investigation of GST gene polymorphisms indicates that GSTM1 and GSTT null alleles are associated with predisposition for COPD and they do not appear to play a substantial role in susceptibility to BA. However, homozygote +/+ and heterozygote +/0 genotypes of GSTT1 revealed to be associated with increasing of IgE level in serum in BA patients. Our findings suggest that the 105Val variant of GSTP1 contributed to the increasing risk of developing of both diseases, and more likely for COPD." @default.
- W771337024 created "2016-06-24" @default.
- W771337024 creator A5043934522 @default.
- W771337024 creator A5088595565 @default.
- W771337024 date "2011-01-01" @default.
- W771337024 modified "2023-09-26" @default.
- W771337024 title "Association of Xenobiotic Detoxification Enzymes Gene Polymorphism in Predisposition of Bronchial Asthma and Chronic Obstructive Pulmonary Disease" @default.
- W771337024 cites W1968792524 @default.
- W771337024 cites W1981681632 @default.
- W771337024 cites W1989327131 @default.
- W771337024 cites W2001207600 @default.
- W771337024 cites W2016275477 @default.
- W771337024 cites W2026277330 @default.
- W771337024 cites W2034011127 @default.
- W771337024 cites W2040197563 @default.
- W771337024 cites W2052649375 @default.
- W771337024 cites W2053798956 @default.
- W771337024 cites W2076792143 @default.
- W771337024 cites W2079962673 @default.
- W771337024 cites W2082942401 @default.
- W771337024 cites W2100756021 @default.
- W771337024 cites W2136923459 @default.
- W771337024 cites W2160487532 @default.
- W771337024 hasPublicationYear "2011" @default.
- W771337024 type Work @default.
- W771337024 sameAs 771337024 @default.
- W771337024 citedByCount "0" @default.
- W771337024 crossrefType "journal-article" @default.
- W771337024 hasAuthorship W771337024A5043934522 @default.
- W771337024 hasAuthorship W771337024A5088595565 @default.
- W771337024 hasConcept C104317684 @default.
- W771337024 hasConcept C126322002 @default.
- W771337024 hasConcept C135763542 @default.
- W771337024 hasConcept C149737253 @default.
- W771337024 hasConcept C153471976 @default.
- W771337024 hasConcept C180754005 @default.
- W771337024 hasConcept C181199279 @default.
- W771337024 hasConcept C203014093 @default.
- W771337024 hasConcept C2776042228 @default.
- W771337024 hasConcept C2776780178 @default.
- W771337024 hasConcept C2776907368 @default.
- W771337024 hasConcept C2779134260 @default.
- W771337024 hasConcept C2780122483 @default.
- W771337024 hasConcept C538909803 @default.
- W771337024 hasConcept C54355233 @default.
- W771337024 hasConcept C55493867 @default.
- W771337024 hasConcept C67636389 @default.
- W771337024 hasConcept C71924100 @default.
- W771337024 hasConcept C76252995 @default.
- W771337024 hasConcept C86803240 @default.
- W771337024 hasConceptScore W771337024C104317684 @default.
- W771337024 hasConceptScore W771337024C126322002 @default.
- W771337024 hasConceptScore W771337024C135763542 @default.
- W771337024 hasConceptScore W771337024C149737253 @default.
- W771337024 hasConceptScore W771337024C153471976 @default.
- W771337024 hasConceptScore W771337024C180754005 @default.
- W771337024 hasConceptScore W771337024C181199279 @default.
- W771337024 hasConceptScore W771337024C203014093 @default.
- W771337024 hasConceptScore W771337024C2776042228 @default.
- W771337024 hasConceptScore W771337024C2776780178 @default.
- W771337024 hasConceptScore W771337024C2776907368 @default.
- W771337024 hasConceptScore W771337024C2779134260 @default.
- W771337024 hasConceptScore W771337024C2780122483 @default.
- W771337024 hasConceptScore W771337024C538909803 @default.
- W771337024 hasConceptScore W771337024C54355233 @default.
- W771337024 hasConceptScore W771337024C55493867 @default.
- W771337024 hasConceptScore W771337024C67636389 @default.
- W771337024 hasConceptScore W771337024C71924100 @default.
- W771337024 hasConceptScore W771337024C76252995 @default.
- W771337024 hasConceptScore W771337024C86803240 @default.
- W771337024 hasLocation W7713370241 @default.
- W771337024 hasOpenAccess W771337024 @default.
- W771337024 hasPrimaryLocation W7713370241 @default.
- W771337024 hasRelatedWork W1518785570 @default.
- W771337024 hasRelatedWork W1983393049 @default.
- W771337024 hasRelatedWork W2021211194 @default.
- W771337024 hasRelatedWork W2031244478 @default.
- W771337024 hasRelatedWork W2074906159 @default.
- W771337024 hasRelatedWork W2079994742 @default.
- W771337024 hasRelatedWork W2091805249 @default.
- W771337024 hasRelatedWork W2104198624 @default.
- W771337024 hasRelatedWork W2132404933 @default.
- W771337024 hasRelatedWork W2136670388 @default.
- W771337024 hasRelatedWork W2162607076 @default.
- W771337024 hasRelatedWork W2168655387 @default.
- W771337024 hasRelatedWork W2262517378 @default.
- W771337024 hasRelatedWork W2401590427 @default.
- W771337024 hasRelatedWork W2414668085 @default.
- W771337024 hasRelatedWork W2914354403 @default.
- W771337024 hasRelatedWork W2994553258 @default.
- W771337024 hasRelatedWork W3140814586 @default.
- W771337024 hasRelatedWork W3151665957 @default.
- W771337024 hasRelatedWork W3152387195 @default.
- W771337024 isParatext "false" @default.
- W771337024 isRetracted "false" @default.
- W771337024 magId "771337024" @default.
- W771337024 workType "article" @default.