Matches in SemOpenAlex for { <https://semopenalex.org/work/W77157423> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W77157423 endingPage "9" @default.
- W77157423 startingPage "25" @default.
- W77157423 abstract "To study effects of a selective beta1-adrenoblocker (B1AB) bisoprolol fumarate (conkor, Nikomed, Germany) on severity of pulmonary hypertension (PH), bronchial obstruction and bioelectric activity of the myocardium in patients with chronic obstructive pulmonary disease (COPD) associated with ischemic heart disease (IHD).Effects of an 8-week course of bisoprolol therapy on pulmonary hypertension, its efficacy and safety were studied in 30 IHD patients with COPD of stage III-IV on broncholytic therapy. The comparison group consisted of 45 IHD patients with COPD untreated with basic bisoprolol therapy. The following parameters were assessed: chest x-ray data, mean pulmonary artery pressure (MPAP) by echocardiography findings, frequency of anginal attacks by ECG monitoring, bronchial permeability by investigation of external respiration function, partial pressure and carbonic gas in blood, oxygen blood saturation (pO2, pCO2 and SaO2).Bisoprolol has decreased MPAP from 23.8 +/- 0.8 mmHg to 21.9 +/- 1.0 mmHg, by 8%, p < 0.05; frequency of anginal attacks, heart rate from 82.2 +/- 1.4 to 73.2 +/- 1.5 b/min; number of episodes of ST segment depression from 2.35 +/- 0.43 to 0.95 +/- 0.22, p < 0.01; total duration of ST segment depression from 10.1 +/- 2.54 to 2.89 +/- 0.76 min, p < 0.01; number of supraventricular and ventricular extrasystoles for 24 hours from 194.5 +/- 74.4 to 96.2 +/- 27.4 and from 239.1 +/- 124.9 to 111.3 +/- 44.1, respectively. Parameters of a 6 min walk test improved from 326.7 to 442 m, p < 0.01. Bisoprolol had no negative effect on bronchial obstruction.Bisoprolol is well tolerated, effective and safe in COPD patients with IHD." @default.
- W77157423 created "2016-06-24" @default.
- W77157423 creator A5001077572 @default.
- W77157423 creator A5026086389 @default.
- W77157423 date "2007-01-01" @default.
- W77157423 modified "2023-09-23" @default.
- W77157423 title "[Efficacy of a cardioselective beta1-adrenoblocker bisoprolol in patients with chronic obstructive pulmonary disease in combination with ischemic heart disease]." @default.
- W77157423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17526191" @default.
- W77157423 hasPublicationYear "2007" @default.
- W77157423 type Work @default.
- W77157423 sameAs 77157423 @default.
- W77157423 citedByCount "2" @default.
- W77157423 countsByYear W771574232012 @default.
- W77157423 countsByYear W771574232021 @default.
- W77157423 crossrefType "journal-article" @default.
- W77157423 hasAuthorship W77157423A5001077572 @default.
- W77157423 hasAuthorship W77157423A5026086389 @default.
- W77157423 hasConcept C126322002 @default.
- W77157423 hasConcept C164705383 @default.
- W77157423 hasConcept C2776780178 @default.
- W77157423 hasConcept C2778213512 @default.
- W77157423 hasConcept C2779670145 @default.
- W77157423 hasConcept C2780630273 @default.
- W77157423 hasConcept C2780930700 @default.
- W77157423 hasConcept C42219234 @default.
- W77157423 hasConcept C71924100 @default.
- W77157423 hasConcept C84393581 @default.
- W77157423 hasConceptScore W77157423C126322002 @default.
- W77157423 hasConceptScore W77157423C164705383 @default.
- W77157423 hasConceptScore W77157423C2776780178 @default.
- W77157423 hasConceptScore W77157423C2778213512 @default.
- W77157423 hasConceptScore W77157423C2779670145 @default.
- W77157423 hasConceptScore W77157423C2780630273 @default.
- W77157423 hasConceptScore W77157423C2780930700 @default.
- W77157423 hasConceptScore W77157423C42219234 @default.
- W77157423 hasConceptScore W77157423C71924100 @default.
- W77157423 hasConceptScore W77157423C84393581 @default.
- W77157423 hasIssue "3" @default.
- W77157423 hasLocation W771574231 @default.
- W77157423 hasOpenAccess W77157423 @default.
- W77157423 hasPrimaryLocation W771574231 @default.
- W77157423 hasRelatedWork W1965466849 @default.
- W77157423 hasRelatedWork W1968763737 @default.
- W77157423 hasRelatedWork W2061508526 @default.
- W77157423 hasRelatedWork W2089064450 @default.
- W77157423 hasRelatedWork W2090518947 @default.
- W77157423 hasRelatedWork W2172009181 @default.
- W77157423 hasRelatedWork W2362808561 @default.
- W77157423 hasRelatedWork W2944702342 @default.
- W77157423 hasRelatedWork W3141700921 @default.
- W77157423 hasRelatedWork W4220731918 @default.
- W77157423 hasVolume "79" @default.
- W77157423 isParatext "false" @default.
- W77157423 isRetracted "false" @default.
- W77157423 magId "77157423" @default.
- W77157423 workType "article" @default.