Matches in SemOpenAlex for { <https://semopenalex.org/work/W771780660> ?p ?o ?g. }
Showing items 1 to 41 of
41
with 100 items per page.
- W771780660 endingPage "393" @default.
- W771780660 startingPage "391" @default.
- W771780660 abstract "目的研制HIV-1／2抗体和P24抗原联合检测酶免疫试剂盒并评价其实用性。方法联合使用基因工程HIVI／2型抗原和抗HIVP24单克隆抗体包被酶联反应板，以辣根过氧化物酶标记的HIVI／2型抗原和生物素化的兔抗HIVP24抗体作为标记物，研制了联合检测HIVI／2抗体和P24抗原的ELISA诊断试剂，并对其特异性、敏感性、稳定性等进行评价和临床考评。结果检测P24抗原质控品的灵敏度可达0．2ng／ml；与雅培公司试剂比较检测78份AIDS患者血清和85份正常人血清、对照检测中国药品生物制品检定所研制的HIV参比血清，特异度和灵敏度均为100％。临床考核检测12051份各种血清，灵敏度为100％（543／543），特异度为99．48％（11448／11508）。试剂在37℃放置6d后，试验结果无明显差异。结论本试剂盒具备特异度强、敏感度高、稳定性好、操作简便等优点，可以一步检出HIV特异性抗体和HIVP24抗原，缩短了HIV感染的检测窗口期，适用于HIV感染的实验室诊断和流行病学调查。" @default.
- W771780660 created "2016-06-24" @default.
- W771780660 creator A5003200557 @default.
- W771780660 creator A5010890161 @default.
- W771780660 creator A5036279331 @default.
- W771780660 creator A5057833769 @default.
- W771780660 creator A5063592586 @default.
- W771780660 creator A5066382722 @default.
- W771780660 creator A5067419853 @default.
- W771780660 creator A5070048314 @default.
- W771780660 creator A5077422844 @default.
- W771780660 date "2007-01-01" @default.
- W771780660 modified "2023-09-23" @default.
- W771780660 title "HIV-1／2抗体和P24抗原联合检测试剂盒的研制与评价" @default.
- W771780660 hasPublicationYear "2007" @default.
- W771780660 type Work @default.
- W771780660 sameAs 771780660 @default.
- W771780660 citedByCount "0" @default.
- W771780660 crossrefType "journal-article" @default.
- W771780660 hasAuthorship W771780660A5003200557 @default.
- W771780660 hasAuthorship W771780660A5010890161 @default.
- W771780660 hasAuthorship W771780660A5036279331 @default.
- W771780660 hasAuthorship W771780660A5057833769 @default.
- W771780660 hasAuthorship W771780660A5063592586 @default.
- W771780660 hasAuthorship W771780660A5066382722 @default.
- W771780660 hasAuthorship W771780660A5067419853 @default.
- W771780660 hasAuthorship W771780660A5070048314 @default.
- W771780660 hasAuthorship W771780660A5077422844 @default.
- W771780660 hasConcept C41008148 @default.
- W771780660 hasConceptScore W771780660C41008148 @default.
- W771780660 hasIssue "4" @default.
- W771780660 hasLocation W7717806601 @default.
- W771780660 hasOpenAccess W771780660 @default.
- W771780660 hasPrimaryLocation W7717806601 @default.
- W771780660 hasVolume "21" @default.
- W771780660 isParatext "false" @default.
- W771780660 isRetracted "false" @default.
- W771780660 magId "771780660" @default.
- W771780660 workType "article" @default.