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- W772637267 abstract "The combination of chemotherapy with all-trans retinoic acid (ATRA) improved prognosis of acute promyelocytic leukemia (APL) when compared to treatment concepts with chemotherapy alone before the availability of ATRA. Using ATRA as single agent complete hematological remission (CR) rates over 90% were achieved. However, cure was only possible, if ATRA was combined with a potent chemotherapy. These observations suggest that the antileukemic effectiveness of the chemotherapy is of critical importance for cure. Therefore, it was the concept of the present study of the AMLCG for patients with newly diagnosed APL to integrate the positive effects of the differentiating substance, ATRA, into a chemotherapy strategy of proven high curative potential." @default.
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- W772637267 date "2003-01-01" @default.
- W772637267 modified "2023-09-26" @default.
- W772637267 title "Therapy of Newly Diagnosed Acute Promyelocytic Leukemia. Results of the AMLCG" @default.
- W772637267 cites W1515269506 @default.
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- W772637267 doi "https://doi.org/10.1007/978-3-642-59358-1_63" @default.
- W772637267 hasPublicationYear "2003" @default.
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