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- W773768896 abstract "The primary objective of this study was to synthesize three types of cross-linked chitosan polymers and further investigate their adsorption capability for multiple mycotoxins, including aflatoxin B1 (AFB1), ochratoxin A (OTA), zearalenone (ZEN), fumonisin B1 (FB1), deoxynivalenol (DON) and T-2 toxin (T2). Among these synthetic adsorbents, cross-linked chitosan-glutaraldehyde complex presented the highest adsorption capability for AFB1 (73%), OTA (97%), ZEN (94%) and FB1 (99%), but no obvious adsorption for DON and T2 (<30%). The effect of various incubation conditions (contact time, dosage and pH) was also studied. Subsequently, the experimental data were fitted to Langmuir, Freundlich and Hill models. The best fitting model to describe AFB1 and FB1 adsorption was Langmuir model (R2 ≥ 0.99), with the theoretical maximum adsorption amounts of 5.67 mg/g for AFB1 and 15.7 mg/g for FB1. The Hill model was the best model for OTA and ZEN adsorption (R2 > 0.98), with the predicted maximum adsorption amounts were 24.8 mg/g for OTA and 9.18 mg/g for ZEN. In addition, the adsorption capability of adsorbent for the simultaneous presence of multiple mycotoxins was also evaluated in buffer system and simulated gastrointestinal condition. The results indicated that the coexisted multiple mycotoxins didn't affected the adsorption capability of adsorbent, whereas the adsorption amounts of toxins were decreased by some gastrointestinal components. The findings of this research suggest that chitosan–glutaraldehyde complex has the potential to be applied as multitoxin adsorbent material for reducing the combined adverse effect of multiple mycotoxins on humans and animals." @default.
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- W773768896 date "2015-11-01" @default.
- W773768896 modified "2023-10-12" @default.
- W773768896 title "Cross-linked chitosan polymers as generic adsorbents for simultaneous adsorption of multiple mycotoxins" @default.
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- W773768896 doi "https://doi.org/10.1016/j.foodcont.2015.05.014" @default.
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