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- W77393130 abstract "This chapter describes immune modulating therapies for idiopathic inflammatory bowel disease. Continued advances in the therapeutics for idiopathic inflammatory bowel diseases reflect the progress that is made in the understanding of the pathogenesis of these disorders. The availability of powerful molecular genetic and cell biological laboratory-investigational techniques has created opportunities to uncover basic causes of these diseases that may lead to singular-curative therapies. A fundamental understanding of the biology of the Crohn's disease and ulcerative colitis can form the basis for therapeutic interventions that are more successful than those available today. More specific drugs that can interrupt immune-mediated tissue destruction may become available as knowledge of the regulation of systemic and local mucosal immune response is discussed in the chapter. Better appreciation of microbial ecology of the intestinal lumen and altered mucosal-barrier function may lead to other treatment approaches involving a coupling of the first-line immune modulating and anti-inflammatory therapies with antibiotics and agents that help restitute the mucosal-barrier epithelium." @default.
- W77393130 created "2016-06-24" @default.
- W77393130 creator A5009322004 @default.
- W77393130 date "1994-01-01" @default.
- W77393130 modified "2023-09-25" @default.
- W77393130 title "Immune Modulating Therapies for Idiopathic Inflammatory Bowel Diseases" @default.
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