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- W77454026 abstract "Cnidarian taxa, currently of the most morphologically simplest extant metazoans, exhibit many salient properties of innate immunity that are shared by most Animalia. One hallmark constituent of immunity exhibit by most cnidarians is histocompatibility, marked by wide spectrum of allogeneic and xenogeneic effector arms, progressing into tissue fusions oRinflammatory rejections. Scientific propensity on cnidarians immunity, while discussing historecognition as the ground for immunity in these organisms, concentrates on host-parasitic and disease oriented studies, or focuses on genome approaches that search for gene homologies with the vertebrates. Above tendency for mixing up between historecognition and host-parasitic/disease, highlights a serious obstacle for the progress in our understanding of cnidarian immunobiology. Here I critically overview four ‘forgotten’ cnidarian immune features, namely, specificity, immunological memory, allogeneic maturation and natural chimerism, presenting insights into perspectives that are prerequisite for any discussion on cnidarian evolution. It is evident that cnidarian historecognition embraces elements that the traditional field of vertebrate immunology has never encountered (i.e., variety of cytotoxic outcomes, different types of effector mechanisms, chimerism, etc.). Also, cnidarian immune features dictating that different individuals within the same species seem to respond differently to the same immunological challenge, is far from that recorded in the vertebrates’ adaptive immunity. While above features may be connected to host-parasitic and disease phenomena and effector arms, they clearly attest to their unique critical roles in shaping cnidarians historecognition, calling for improved distinction between historecognition and host-response/ disease disciplines. The research on cnidarians immunity still suffers from the lack of accepted synthesis of what historecognition is or does. Mounting of an immune response against conspecifics or xenogeneic organisms should therefore be clearly demarcated from other paths of immunity, till cnidarian innate immunity as a whole is expounded." @default.
- W77454026 created "2016-06-24" @default.
- W77454026 creator A5090421412 @default.
- W77454026 date "2012-01-01" @default.
- W77454026 modified "2023-09-27" @default.
- W77454026 title "Neglected Biological Features in Cnidarians Self-Nonself Recognition" @default.
- W77454026 cites W1830460099 @default.
- W77454026 cites W1965688385 @default.
- W77454026 cites W1965778925 @default.
- W77454026 cites W1966345914 @default.
- W77454026 cites W1973478589 @default.
- W77454026 cites W1975017547 @default.
- W77454026 cites W1976611543 @default.
- W77454026 cites W1978043888 @default.
- W77454026 cites W1979160303 @default.
- W77454026 cites W1982844071 @default.
- W77454026 cites W1986190311 @default.
- W77454026 cites W1988039504 @default.
- W77454026 cites W1989424164 @default.
- W77454026 cites W1994544006 @default.
- W77454026 cites W1997730102 @default.
- W77454026 cites W2005452204 @default.
- W77454026 cites W2005682388 @default.
- W77454026 cites W2007836513 @default.
- W77454026 cites W2008460182 @default.
- W77454026 cites W2011010663 @default.
- W77454026 cites W2017771577 @default.
- W77454026 cites W2021477184 @default.
- W77454026 cites W2023887150 @default.
- W77454026 cites W2028080887 @default.
- W77454026 cites W2034440237 @default.
- W77454026 cites W2040952833 @default.
- W77454026 cites W2048559125 @default.
- W77454026 cites W2048903990 @default.
- W77454026 cites W2049389010 @default.
- W77454026 cites W2049597094 @default.
- W77454026 cites W2051169173 @default.
- W77454026 cites W2052036866 @default.
- W77454026 cites W2055483179 @default.
- W77454026 cites W2058680734 @default.
- W77454026 cites W2059015755 @default.
- W77454026 cites W2061509048 @default.
- W77454026 cites W2067451449 @default.
- W77454026 cites W2069140648 @default.
- W77454026 cites W2070128421 @default.
- W77454026 cites W2071667733 @default.
- W77454026 cites W2076271968 @default.
- W77454026 cites W2077602020 @default.
- W77454026 cites W2077684668 @default.
- W77454026 cites W2078634356 @default.
- W77454026 cites W2085429789 @default.
- W77454026 cites W2085720184 @default.
- W77454026 cites W2087828921 @default.
- W77454026 cites W2089593962 @default.
- W77454026 cites W2091065429 @default.
- W77454026 cites W2091699395 @default.
- W77454026 cites W2091957158 @default.
- W77454026 cites W2092814014 @default.
- W77454026 cites W2094092147 @default.
- W77454026 cites W2107997395 @default.
- W77454026 cites W2108956223 @default.
- W77454026 cites W2109870801 @default.
- W77454026 cites W2110578274 @default.
- W77454026 cites W2118158639 @default.
- W77454026 cites W2119016898 @default.
- W77454026 cites W2120470757 @default.
- W77454026 cites W2121592635 @default.
- W77454026 cites W2124602794 @default.
- W77454026 cites W2125202839 @default.
- W77454026 cites W2125983730 @default.
- W77454026 cites W2143692667 @default.
- W77454026 cites W2146655781 @default.
- W77454026 cites W2148461722 @default.
- W77454026 cites W2152252309 @default.
- W77454026 cites W2154661771 @default.
- W77454026 cites W2155011586 @default.
- W77454026 cites W2156237707 @default.
- W77454026 cites W2169596009 @default.
- W77454026 cites W2171582068 @default.
- W77454026 cites W2334862509 @default.
- W77454026 cites W42274204 @default.
- W77454026 cites W4241147990 @default.
- W77454026 cites W4246258666 @default.
- W77454026 cites W4255786081 @default.
- W77454026 doi "https://doi.org/10.1007/978-1-4614-1680-7_4" @default.
- W77454026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22399373" @default.
- W77454026 hasPublicationYear "2012" @default.
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