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- W77479537 abstract "Endocrine disruptors are exogenous natural or anthropogenic agents that produce adverse effects not only at the level of the individual, but also of the population and the community, by interfering with endogenous hormones in the body. Since these hormones are responsible for key processes in cellular control and communication as well as reproduction, development and behaviour, several severe impacts on ecosystems that occured during the last fifty years can now be explained by the presence of hormone mimics, acting as endocrine disruptors. Xenoestrogens such as DDT and PCBs are of special importance because they are leading to “feminized” wild life. Some of them are suspect of causing human sperm abnormalities, a decrease in sperm counts and a rise in hormone-related cancers. Since embryo development is particularly sensitive to estrogens, even small shifts in hormone levels experienced during the embryonic stage, e.g. by the presence of xenoestrogens, can cause malformations and cancer. The best known example is diethylstilbestrol (DES), a human “transplacental” carcinogen." @default.
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- W77479537 date "1998-01-01" @default.
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- W77479537 title "Endocrine Disruptors: Monitoring of Effects" @default.
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