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- W775284585 abstract "• This study examined the effects of reduced DBS stimulation on the severity of PD symptoms. • Significant changes were seen in the clinical scores across varied DBS conditions. • The majority of symptoms increased in severity as the DBS frequency was reduced (p-value <0.05). • Total Clinical Score (i.e., the cumulative score of the severity of symptoms) increased as the DBS frequency was reduced (p-value of 0.001). • HY Staging values also increased with decreasing frequencies (p-value of 0.03). • These results are supportive of what we expected; that as you decrease the frequency of DBS from the patients’ therapeutic setting, the clinical symptoms worsen (become more severe). • This is an important observation to make so that appropriate clinical decisions can be made as we continue to investigate the effects of reduced frequency DBS on gait and posture control. • It is likely that the potential improvements in gait and posture control at reduced DBS frequencies will have to weighed against the increase in PD clinical severity. • A limitation of this study includes sample size. Twelve subjects were studied, however, patient recruitment and data collection is ongoing. Methods" @default.
- W775284585 created "2016-06-24" @default.
- W775284585 creator A5070721306 @default.
- W775284585 date "2015-04-01" @default.
- W775284585 modified "2023-09-23" @default.
- W775284585 title "EFFECTS OF REDUCED DEEP BRAIN STIMULATION FREQUENCIES IN PARKINSON’S DISEASE" @default.
- W775284585 hasPublicationYear "2015" @default.
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