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- W77669310 abstract "The term ‘antisocial substance dependence (ASD)’ may name a categorical diagnosis, combining antisocial personality disorder and substance dependence, or it may name the extreme end of an externalizing trait of behavioral disinhibition. Genes strongly influence ASD, presumably by altering brain structure and function. Environmental adversity and substance toxicity may also exacerbate ASD. Hypofunction in a neural network regulating risk-taking behavior in such persons apparently contributes to their high-risk antisocial and substance-using behaviors. Treatment is effective in the short run, but the underlying brain disorder and behavioral disinhibition remain detectable during treatment, presumably contributing to frequent relapses." @default.
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- W77669310 date "2010-01-01" @default.
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- W77669310 title "Antisocial Substance Dependence" @default.
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- W77669310 doi "https://doi.org/10.1016/b978-0-08-045396-5.00060-9" @default.
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