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- W77690139 abstract "Abstract Hyaluronan (hyaluronic acid) solutions are widely used in medicinal applications due to their biological compatibility and rheological properties. This work uses the technique NMR velocity imaging to study the flow behaviour of hyaluronan solutions pumped through Teflon tubing. Three commercially available hyaluronan solutions, (Healon ® , Healon ® GV and Healon ® 5) were investigated along with a set of samples with concentrations ranging from 1 to 23 mg ml −1 and weight average molecular weight, M w , between 0.3 and 5.2×10 6 . The shape of the velocity profiles were found to vary significantly with M w , concentration and apparent shear rate. Transitions were observed from near Newtonian flow to shear thinning to wall slip with increasing M w and concentration. Solutions with the highest M w and concentration showed possible ‘shear banding’ effects in addition to wall slip with a distinctive region of high shear with an annulus of around 50 μm at the edge of the tube." @default.
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- W77690139 date "2002-02-01" @default.
- W77690139 modified "2023-09-26" @default.
- W77690139 title "NMR velocity imaging of the flow behaviour of hyaluronan solutions" @default.
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- W77690139 doi "https://doi.org/10.1016/s0144-8617(01)00183-7" @default.
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