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- W778562142 abstract "Recent studies have revealed that the intestinal microbiota plays an important role in host physiology and pathophysiology in health and disease. One of the major mechanisms by which the gut microbiota influences the host is through its interactions with and effects on the host immune system. In this review, we discuss the reciprocal interactions between the host immune system and the gut microbiota, with a particular focus on individual microbes that impact the host through dramatic and specific interactions with the adaptive immune system. We highlight the idea that the presence or absence of specific immunologically important members of the microbiota can determine disease susceptibility and propose that the identification and characterization of these bacteria in humans will eventually allow us to elucidate the role of microbiota composition in human disease." @default.
- W778562142 created "2016-06-24" @default.
- W778562142 creator A5022058492 @default.
- W778562142 creator A5025062503 @default.
- W778562142 creator A5033791252 @default.
- W778562142 date "2015-08-01" @default.
- W778562142 modified "2023-10-13" @default.
- W778562142 title "Immune–microbiota interactions in health and disease" @default.
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- W778562142 doi "https://doi.org/10.1016/j.clim.2015.05.014" @default.
- W778562142 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4943041" @default.
- W778562142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26141651" @default.
- W778562142 hasPublicationYear "2015" @default.
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