FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W778834470> ?p ?o ?g. }

• W778834470 abstract "The gut microbiota is commonly referred to as a hidden organ due to its pivotal effects on host physiology, metabolism, nutrition and immunity. The gut microbes may be shaped by environmental and host genetic factors, and previous studies have focused on the roles of protein-coding genes. Here we show a link between long non-coding RNA (lncRNA) expression and gut microbes. By repurposing exon microarrays and comparing the lncRNA expression profiles between germ-free, conventional and different gnotobiotic mice, we revealed subgroups of lncRNAs that were specifically enriched in each condition. A nearest shrunken centroid methodology was applied to obtain lncRNA-based signatures to identify mice in different conditions. The lncRNA-based prediction model successfully identified different gnotobiotic mice from conventional and germ-free mice, and also discriminated mice harboring transplanted microbes from fecal samples of mice or zebra fishes. To achieve optimal prediction accuracy, fewer lncRNAs were required in the prediction model than protein-coding genes. Taken together, our study demonstrated the effecacy of lncRNA expression profiles in discriminating the types of microbes in the gut. These results also provide a resource of gut microbe-associated lncRNAs for the development of lncRNA biomarkers and the identification of functional lncRNAs in host-microbes interactions." @default.
• W778834470 created "2016-06-24" @default.
• W778834470 creator A5003564309 @default.
• W778834470 creator A5005496208 @default.
• W778834470 creator A5048704005 @default.
• W778834470 creator A5051505252 @default.
• W778834470 creator A5088006824 @default.
• W778834470 date "2015-06-30" @default.
• W778834470 modified "2023-10-17" @default.
• W778834470 title "Long noncoding RNA expression profiles in gut tissues constitute molecular signatures that reflect the types of microbes" @default.
• W778834470 cites W1596937937 @default.
• W778834470 cites W181316119 @default.
• W778834470 cites W1965024447 @default.
• W778834470 cites W1966311917 @default.
• W778834470 cites W1969839871 @default.
• W778834470 cites W1974930518 @default.
• W778834470 cites W1979258768 @default.
• W778834470 cites W1998465679 @default.
• W778834470 cites W1998585946 @default.
• W778834470 cites W2003269843 @default.
• W778834470 cites W2010637767 @default.
• W778834470 cites W2015104432 @default.
• W778834470 cites W2019902544 @default.
• W778834470 cites W2024192805 @default.
• W778834470 cites W2031205682 @default.
• W778834470 cites W2054208291 @default.
• W778834470 cites W2055203030 @default.
• W778834470 cites W2060536393 @default.
• W778834470 cites W2067433711 @default.
• W778834470 cites W2077506769 @default.
• W778834470 cites W2078770291 @default.
• W778834470 cites W2090711753 @default.
• W778834470 cites W2092696502 @default.
• W778834470 cites W2096891797 @default.
• W778834470 cites W2097704232 @default.
• W778834470 cites W2098762803 @default.
• W778834470 cites W2099297431 @default.
• W778834470 cites W2108051165 @default.
• W778834470 cites W2128371193 @default.
• W778834470 cites W2133644362 @default.
• W778834470 cites W2135695964 @default.
• W778834470 cites W2138550913 @default.
• W778834470 cites W2146512944 @default.
• W778834470 cites W2149093044 @default.
• W778834470 cites W2149627698 @default.
• W778834470 cites W2150253265 @default.
• W778834470 cites W2153882021 @default.
• W778834470 cites W2154623878 @default.
• W778834470 cites W2158804744 @default.
• W778834470 cites W4232035514 @default.
• W778834470 cites W45534775 @default.
• W778834470 doi "https://doi.org/10.1038/srep11763" @default.
• W778834470 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4485256" @default.
• W778834470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26123364" @default.
• W778834470 hasPublicationYear "2015" @default.
• W778834470 type Work @default.
• W778834470 sameAs 778834470 @default.
• W778834470 citedByCount "63" @default.
• W778834470 countsByYear W7788344702015 @default.
• W778834470 countsByYear W7788344702016 @default.
• W778834470 countsByYear W7788344702017 @default.
• W778834470 countsByYear W7788344702018 @default.
• W778834470 countsByYear W7788344702019 @default.
• W778834470 countsByYear W7788344702020 @default.
• W778834470 countsByYear W7788344702021 @default.
• W778834470 countsByYear W7788344702022 @default.
• W778834470 countsByYear W7788344702023 @default.
• W778834470 crossrefType "journal-article" @default.
• W778834470 hasAuthorship W778834470A5003564309 @default.
• W778834470 hasAuthorship W778834470A5005496208 @default.
• W778834470 hasAuthorship W778834470A5048704005 @default.
• W778834470 hasAuthorship W778834470A5051505252 @default.
• W778834470 hasAuthorship W778834470A5088006824 @default.
• W778834470 hasBestOaLocation W7788344701 @default.
• W778834470 hasConcept C104317684 @default.
• W778834470 hasConcept C150194340 @default.
• W778834470 hasConcept C162317418 @default.
• W778834470 hasConcept C203014093 @default.
• W778834470 hasConcept C539455810 @default.
• W778834470 hasConcept C54355233 @default.
• W778834470 hasConcept C62203573 @default.
• W778834470 hasConcept C67705224 @default.
• W778834470 hasConcept C70721500 @default.
• W778834470 hasConcept C86803240 @default.
• W778834470 hasConcept C95371953 @default.
• W778834470 hasConceptScore W778834470C104317684 @default.
• W778834470 hasConceptScore W778834470C150194340 @default.
• W778834470 hasConceptScore W778834470C162317418 @default.
• W778834470 hasConceptScore W778834470C203014093 @default.
• W778834470 hasConceptScore W778834470C539455810 @default.
• W778834470 hasConceptScore W778834470C54355233 @default.
• W778834470 hasConceptScore W778834470C62203573 @default.
• W778834470 hasConceptScore W778834470C67705224 @default.
• W778834470 hasConceptScore W778834470C70721500 @default.
• W778834470 hasConceptScore W778834470C86803240 @default.
• W778834470 hasConceptScore W778834470C95371953 @default.
• W778834470 hasIssue "1" @default.
• W778834470 hasLocation W7788344701 @default.
• W778834470 hasLocation W7788344702 @default.
• W778834470 hasLocation W7788344703 @default.

• next