Matches in SemOpenAlex for { <https://semopenalex.org/work/W778846459> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W778846459 abstract "Purpose An age-cohort was studied with long-term follow-up. The population was born in 1915, living in the municipality of Skelleftea in 1981. The purpose was to investigate the prevalence and incidence of pseudoexfoliation (PEX), its influence on intraocular pressure (IOP) and development of open-angle glaucoma (OAG). Another purpose was to estimate the value of screening for glaucoma by comparing the screened group within the cohort with the remaining unscreened group.Methods In 1981, 339 (40%) of the 856 individuals in the cohort underwent an eye examination. This screened group was re-examined at seven-year intervals until 2002. At each visit the presence of PEX was registered, IOP was measured and the presence of glaucoma was assessed. After the 21-year follow-up period, glaucoma cases were also searched for in the medical records of the remaining unscreened individuals in the cohort. Proportions of glaucoma were compared between the two groups.Results The prevalence of PEX was 23% (95% confidence interval (CI): 20-26%) at the age of 66 and increased to 61% (CI: 50-71%) at the age of 87. The annual incidence of PEX was 1.8% (CI: 1.3-2.4%). The prevalence of OAG increased from 2.1% (CI: 0.8-4.3%) at the age of 66 years to 25 % (CI: 16-35%) at 87 years. The overall annual incidence of OAG was 0.9% (CI: 0.6-1.3%) and for OAG with PEX 2.1% (CI: 1.2-3.3%). PEX increased the risk of developing glaucoma at least four-fold. The incidence of diagnosed OAG in women was higher in the screened group than in the unscreened group (incidence rate ratio (IRR)=1.94, p=0.035). A corresponding difference could not be verified for men (p=0.58). The mean, agedependent, increase in IOP during the 21-year observation period was 0.05 mmHg/year.Conclusion The prevalence of PEX in this study population was the highest reported, and it increased with age. The presence of PEX increased the risk of developing OAG four times. In this study a higher proportion of OAG was revealed by screening among women but not among men. The age-related IOP increase was clinically insignificant." @default.
- W778846459 created "2016-06-24" @default.
- W778846459 creator A5015009421 @default.
- W778846459 creator A5035554566 @default.
- W778846459 creator A5059171459 @default.
- W778846459 date "2013-01-01" @default.
- W778846459 modified "2023-09-26" @default.
- W778846459 title "Open-angle glaucoma in screened versus unscreened subjects : a long-term age-cohort study" @default.
- W778846459 hasPublicationYear "2013" @default.
- W778846459 type Work @default.
- W778846459 sameAs 778846459 @default.
- W778846459 citedByCount "0" @default.
- W778846459 crossrefType "journal-article" @default.
- W778846459 hasAuthorship W778846459A5015009421 @default.
- W778846459 hasAuthorship W778846459A5035554566 @default.
- W778846459 hasAuthorship W778846459A5059171459 @default.
- W778846459 hasConcept C118487528 @default.
- W778846459 hasConcept C120665830 @default.
- W778846459 hasConcept C121332964 @default.
- W778846459 hasConcept C126322002 @default.
- W778846459 hasConcept C187212893 @default.
- W778846459 hasConcept C201903717 @default.
- W778846459 hasConcept C2778527774 @default.
- W778846459 hasConcept C2781092963 @default.
- W778846459 hasConcept C2908647359 @default.
- W778846459 hasConcept C2991803831 @default.
- W778846459 hasConcept C44249647 @default.
- W778846459 hasConcept C61511704 @default.
- W778846459 hasConcept C71924100 @default.
- W778846459 hasConcept C72563966 @default.
- W778846459 hasConcept C99454951 @default.
- W778846459 hasConceptScore W778846459C118487528 @default.
- W778846459 hasConceptScore W778846459C120665830 @default.
- W778846459 hasConceptScore W778846459C121332964 @default.
- W778846459 hasConceptScore W778846459C126322002 @default.
- W778846459 hasConceptScore W778846459C187212893 @default.
- W778846459 hasConceptScore W778846459C201903717 @default.
- W778846459 hasConceptScore W778846459C2778527774 @default.
- W778846459 hasConceptScore W778846459C2781092963 @default.
- W778846459 hasConceptScore W778846459C2908647359 @default.
- W778846459 hasConceptScore W778846459C2991803831 @default.
- W778846459 hasConceptScore W778846459C44249647 @default.
- W778846459 hasConceptScore W778846459C61511704 @default.
- W778846459 hasConceptScore W778846459C71924100 @default.
- W778846459 hasConceptScore W778846459C72563966 @default.
- W778846459 hasConceptScore W778846459C99454951 @default.
- W778846459 hasLocation W7788464591 @default.
- W778846459 hasOpenAccess W778846459 @default.
- W778846459 hasPrimaryLocation W7788464591 @default.
- W778846459 hasRelatedWork W2002829322 @default.
- W778846459 hasRelatedWork W2006523470 @default.
- W778846459 hasRelatedWork W2008394207 @default.
- W778846459 hasRelatedWork W2066255121 @default.
- W778846459 hasRelatedWork W2080193219 @default.
- W778846459 hasRelatedWork W2088165310 @default.
- W778846459 hasRelatedWork W2101833571 @default.
- W778846459 hasRelatedWork W2104475650 @default.
- W778846459 hasRelatedWork W2121963763 @default.
- W778846459 hasRelatedWork W2138047197 @default.
- W778846459 hasRelatedWork W2145139120 @default.
- W778846459 hasRelatedWork W2159380578 @default.
- W778846459 hasRelatedWork W2161603660 @default.
- W778846459 hasRelatedWork W2165557575 @default.
- W778846459 hasRelatedWork W2185642873 @default.
- W778846459 hasRelatedWork W2381622986 @default.
- W778846459 hasRelatedWork W2582584576 @default.
- W778846459 hasRelatedWork W935059487 @default.
- W778846459 hasRelatedWork W2102847663 @default.
- W778846459 hasRelatedWork W2139267234 @default.
- W778846459 isParatext "false" @default.
- W778846459 isRetracted "false" @default.
- W778846459 magId "778846459" @default.
- W778846459 workType "article" @default.