Matches in SemOpenAlex for { <https://semopenalex.org/work/W77954637> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W77954637 abstract "Environmental changes are known to trigger evolutionary changes, e.g. by favoring higher mutation rates. We study the evolutionary dynamics of a delayed stochastic genetic circuit using a simulator developed for this aim. We model a cell population subject to selection and environmental changes. Each cell contains a self-repressing gene whose protein degrades a toxin. Allowing mutations, we study the adaptability of this circuit and how the genotypic and phenotypic diversities of the population evolve. Neutral mutations and equally beneficial evolutionary pathways are found to generate complex phenotypic distributions. We find optimal mutation rates dependent on the amount of toxin and show that shifting environmental conditions trigger transient increases in diversity. The results support the hypothesis that evolvability is a selectable trait." @default.
- W77954637 created "2016-06-24" @default.
- W77954637 creator A5016780927 @default.
- W77954637 creator A5026230936 @default.
- W77954637 creator A5033673376 @default.
- W77954637 creator A5058631492 @default.
- W77954637 creator A5076316712 @default.
- W77954637 date "2011-01-01" @default.
- W77954637 modified "2023-09-23" @default.
- W77954637 title "Evolutionary Dynamics of a Population of Cells with a Toxin Suppressor Gene" @default.
- W77954637 cites W1966807997 @default.
- W77954637 cites W1967668980 @default.
- W77954637 cites W1978329448 @default.
- W77954637 cites W1996691828 @default.
- W77954637 cites W2011097028 @default.
- W77954637 cites W2014701397 @default.
- W77954637 cites W2026888821 @default.
- W77954637 cites W2039099796 @default.
- W77954637 cites W2042631968 @default.
- W77954637 cites W2045312048 @default.
- W77954637 cites W2069780164 @default.
- W77954637 cites W2118274513 @default.
- W77954637 cites W2123505432 @default.
- W77954637 cites W2137112190 @default.
- W77954637 cites W2148357087 @default.
- W77954637 cites W2152585463 @default.
- W77954637 cites W2155418451 @default.
- W77954637 cites W2170467788 @default.
- W77954637 cites W4241088457 @default.
- W77954637 doi "https://doi.org/10.1007/978-3-642-19748-2_1" @default.
- W77954637 hasPublicationYear "2011" @default.
- W77954637 type Work @default.
- W77954637 sameAs 77954637 @default.
- W77954637 citedByCount "0" @default.
- W77954637 crossrefType "book-chapter" @default.
- W77954637 hasAuthorship W77954637A5016780927 @default.
- W77954637 hasAuthorship W77954637A5026230936 @default.
- W77954637 hasAuthorship W77954637A5033673376 @default.
- W77954637 hasAuthorship W77954637A5058631492 @default.
- W77954637 hasAuthorship W77954637A5076316712 @default.
- W77954637 hasConcept C104317684 @default.
- W77954637 hasConcept C106934330 @default.
- W77954637 hasConcept C127716648 @default.
- W77954637 hasConcept C144024400 @default.
- W77954637 hasConcept C149923435 @default.
- W77954637 hasConcept C171578705 @default.
- W77954637 hasConcept C176147130 @default.
- W77954637 hasConcept C177606310 @default.
- W77954637 hasConcept C18903297 @default.
- W77954637 hasConcept C199360897 @default.
- W77954637 hasConcept C2908647359 @default.
- W77954637 hasConcept C41008148 @default.
- W77954637 hasConcept C501734568 @default.
- W77954637 hasConcept C54355233 @default.
- W77954637 hasConcept C86803240 @default.
- W77954637 hasConcept C98638677 @default.
- W77954637 hasConceptScore W77954637C104317684 @default.
- W77954637 hasConceptScore W77954637C106934330 @default.
- W77954637 hasConceptScore W77954637C127716648 @default.
- W77954637 hasConceptScore W77954637C144024400 @default.
- W77954637 hasConceptScore W77954637C149923435 @default.
- W77954637 hasConceptScore W77954637C171578705 @default.
- W77954637 hasConceptScore W77954637C176147130 @default.
- W77954637 hasConceptScore W77954637C177606310 @default.
- W77954637 hasConceptScore W77954637C18903297 @default.
- W77954637 hasConceptScore W77954637C199360897 @default.
- W77954637 hasConceptScore W77954637C2908647359 @default.
- W77954637 hasConceptScore W77954637C41008148 @default.
- W77954637 hasConceptScore W77954637C501734568 @default.
- W77954637 hasConceptScore W77954637C54355233 @default.
- W77954637 hasConceptScore W77954637C86803240 @default.
- W77954637 hasConceptScore W77954637C98638677 @default.
- W77954637 hasLocation W779546371 @default.
- W77954637 hasOpenAccess W77954637 @default.
- W77954637 hasPrimaryLocation W779546371 @default.
- W77954637 hasRelatedWork W1576017933 @default.
- W77954637 hasRelatedWork W1843632541 @default.
- W77954637 hasRelatedWork W1904261486 @default.
- W77954637 hasRelatedWork W1919433850 @default.
- W77954637 hasRelatedWork W1973641090 @default.
- W77954637 hasRelatedWork W2046709474 @default.
- W77954637 hasRelatedWork W2074946442 @default.
- W77954637 hasRelatedWork W2081938446 @default.
- W77954637 hasRelatedWork W2097592200 @default.
- W77954637 hasRelatedWork W2119228920 @default.
- W77954637 hasRelatedWork W2122350660 @default.
- W77954637 hasRelatedWork W2122948387 @default.
- W77954637 hasRelatedWork W2145578331 @default.
- W77954637 hasRelatedWork W2147650094 @default.
- W77954637 hasRelatedWork W2158295054 @default.
- W77954637 hasRelatedWork W2158951611 @default.
- W77954637 hasRelatedWork W2953085142 @default.
- W77954637 hasRelatedWork W3134099314 @default.
- W77954637 hasRelatedWork W3187146652 @default.
- W77954637 hasRelatedWork W4206696958 @default.
- W77954637 isParatext "false" @default.
- W77954637 isRetracted "false" @default.
- W77954637 magId "77954637" @default.
- W77954637 workType "book-chapter" @default.