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• W78023028 abstract "Despite a series of elegant studies performed by Beznak in the fifties clearly demonstrating Growth Hormone (GH)’s role in maintaining a normal hypertrophie response following experimental aortic constriction (1-3), the cardiovascular role of the GH/IGF-1 axis was largely overlooked. In fact, until few years ago, GH was classically regarded as the principal mediator of bone linear growth, in addition to its well known actions on glucose homeostasis and skeletal muscle mass, and the heart was not generally considered as a target tissue (4). It is now well established that not only does GH play an essential role in maintaining a normal cardiac muscle mass and function, but also that its growth-promoting and positive inotropic actions may be beneficial in the setting of heart failure and ischemic syndromes." @default.
• W78023028 created "2016-06-24" @default.
• W78023028 creator A5058260855 @default.
• W78023028 creator A5091455165 @default.
• W78023028 date "2001-01-01" @default.
• W78023028 modified "2023-09-23" @default.
• W78023028 title "The Cellular and Molecular Basis for Growth Hormone Action on the Heart" @default.
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• W78023028 doi "https://doi.org/10.1007/978-1-4615-1579-1_1" @default.
• W78023028 hasPublicationYear "2001" @default.
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