Matches in SemOpenAlex for { <https://semopenalex.org/work/W78167578> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W78167578 endingPage "52" @default.
- W78167578 startingPage "46" @default.
- W78167578 abstract "The interrelationship between cardiac hypertrophy induced by increased pressure load and concomitant changes in the myoeardial myosin isoenzyme population was studied. In order to induce severe load on predominantly one ventricle, 6-week-old Wistar rats were fed on seeds of the plant Crotalaria spectabilis for 4 weeks. The ensuing pulmonary hypertension resulted in significant hypertrophy of only the right ventricle (52 %). In contrast, the isoenzyme population of myosin was affected in both ventricles, more so, however, in the right ventricle, as shown by the proportion of ventricular myosin (VM)-3 given as a percentage of the 3 ventricular myosin isoenzymes (right ventricle 29.7 ± 4.8 % VM-3 vs. 20.6 ± 5.3 % VM-3 of left ventricle; VM-3 of left and right ventricles of control rats was 9.3 ± 1.8%). Since thyroid hormones are major determinants of cardiac myosin isoenzymes and since Crotalaria spectabilis also affects other organs beside the lungs, serum thyroxine was determined. The thyroid hormone was significantly reduced, not, however, thyroxine binding index. The results suggest that reduced concentrations of circulating thyroid hormones contribute to the shift towards VM-3 in the myosin isoenzyme population. Since normal adult rats also exhibit an increased proportion of VM-3 in the predominantly loaded ventricle, it is concluded that beside the action of thyroid hormones, other mechanisms are responsible for the expression of the different myosin isoenzymes, such as those arising from altered adrenergic responsiveness and transmitter status of myocardium." @default.
- W78167578 created "2016-06-24" @default.
- W78167578 creator A5019758045 @default.
- W78167578 creator A5032269537 @default.
- W78167578 creator A5048145449 @default.
- W78167578 date "1983-01-01" @default.
- W78167578 modified "2023-09-26" @default.
- W78167578 title "Dissociation between factors resulting in hypertrophy and changes in myosin isoenzyme population of the pressure-loaded rat heart" @default.
- W78167578 cites W1968564818 @default.
- W78167578 cites W1975878727 @default.
- W78167578 cites W1978575714 @default.
- W78167578 cites W1983511446 @default.
- W78167578 cites W1993310251 @default.
- W78167578 cites W2000023960 @default.
- W78167578 cites W2001342018 @default.
- W78167578 cites W2016935307 @default.
- W78167578 cites W2016940224 @default.
- W78167578 cites W2038564114 @default.
- W78167578 cites W2042732734 @default.
- W78167578 cites W2051146620 @default.
- W78167578 cites W2087441680 @default.
- W78167578 cites W2093297854 @default.
- W78167578 cites W2096636937 @default.
- W78167578 cites W2110505018 @default.
- W78167578 cites W2127546896 @default.
- W78167578 cites W2133917504 @default.
- W78167578 cites W2782842503 @default.
- W78167578 doi "https://doi.org/10.1007/978-3-642-85326-5_5" @default.
- W78167578 hasPublicationYear "1983" @default.
- W78167578 type Work @default.
- W78167578 sameAs 78167578 @default.
- W78167578 citedByCount "6" @default.
- W78167578 crossrefType "book-chapter" @default.
- W78167578 hasAuthorship W78167578A5019758045 @default.
- W78167578 hasAuthorship W78167578A5032269537 @default.
- W78167578 hasAuthorship W78167578A5048145449 @default.
- W78167578 hasConcept C126322002 @default.
- W78167578 hasConcept C134018914 @default.
- W78167578 hasConcept C167414201 @default.
- W78167578 hasConcept C185592680 @default.
- W78167578 hasConcept C2778271984 @default.
- W78167578 hasConcept C2778921608 @default.
- W78167578 hasConcept C2908647359 @default.
- W78167578 hasConcept C3018791406 @default.
- W78167578 hasConcept C526584372 @default.
- W78167578 hasConcept C55493867 @default.
- W78167578 hasConcept C6997183 @default.
- W78167578 hasConcept C71315377 @default.
- W78167578 hasConcept C71924100 @default.
- W78167578 hasConcept C86803240 @default.
- W78167578 hasConcept C99454951 @default.
- W78167578 hasConceptScore W78167578C126322002 @default.
- W78167578 hasConceptScore W78167578C134018914 @default.
- W78167578 hasConceptScore W78167578C167414201 @default.
- W78167578 hasConceptScore W78167578C185592680 @default.
- W78167578 hasConceptScore W78167578C2778271984 @default.
- W78167578 hasConceptScore W78167578C2778921608 @default.
- W78167578 hasConceptScore W78167578C2908647359 @default.
- W78167578 hasConceptScore W78167578C3018791406 @default.
- W78167578 hasConceptScore W78167578C526584372 @default.
- W78167578 hasConceptScore W78167578C55493867 @default.
- W78167578 hasConceptScore W78167578C6997183 @default.
- W78167578 hasConceptScore W78167578C71315377 @default.
- W78167578 hasConceptScore W78167578C71924100 @default.
- W78167578 hasConceptScore W78167578C86803240 @default.
- W78167578 hasConceptScore W78167578C99454951 @default.
- W78167578 hasLocation W781675781 @default.
- W78167578 hasOpenAccess W78167578 @default.
- W78167578 hasPrimaryLocation W781675781 @default.
- W78167578 hasRelatedWork W117621442 @default.
- W78167578 hasRelatedWork W2009526181 @default.
- W78167578 hasRelatedWork W2010645160 @default.
- W78167578 hasRelatedWork W2020688170 @default.
- W78167578 hasRelatedWork W2026117978 @default.
- W78167578 hasRelatedWork W2027938488 @default.
- W78167578 hasRelatedWork W2076322483 @default.
- W78167578 hasRelatedWork W2155312245 @default.
- W78167578 hasRelatedWork W2165389221 @default.
- W78167578 hasRelatedWork W2095364283 @default.
- W78167578 isParatext "false" @default.
- W78167578 isRetracted "false" @default.
- W78167578 magId "78167578" @default.
- W78167578 workType "book-chapter" @default.