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• W78348736 abstract "Over the years, various pharmacologic agents have been developed to provide sedation, anxiolysis, and amnesia. These agents have been used both as therapeutic agents (barbiturates to control intracranial pressure, propofol to treat refractory status epilepticus) and to provide sedation, anxiolysis, and amnesia in various clinical scenarios. In the setting of diagnostic and therapeutic procedures, these agents usually are used to induce amnesia and to provide a motionless patient, which may be required to facilitate a procedure or achieve an accurate radiologic examination. When used during invasive and/or diagnostic procedures, although these agents provide amnesia, anxiolysis, and sedation, most except for ketamine possess limited intrinsic analgesic properties and therefore are often combined with an opioid if analgesia is required (see Chapter 7). Although the majority of patients experience few and mild cardiorespiratory effects, these agents can be potent respiratory depressants and may have adverse effects on cardiovascular function. Therefore, these agents should be administered only by those who are well-acquainted with their use and pharmacologic properties and only in a controlled, monitored setting (see Chapter 8). This chapter reviews the more commonly used sedative agents, including propofol, ketamine, the barbiturates, the benzodiazepines, nitrous oxide, and chloral hydrate." @default.
• W78348736 created "2016-06-24" @default.
• W78348736 creator A5048394709 @default.
• W78348736 date "2003-01-01" @default.
• W78348736 modified "2023-09-23" @default.
• W78348736 title "Pharmacology of Sedative Agents" @default.
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• W78348736 doi "https://doi.org/10.1007/978-1-59259-295-1_6" @default.
• W78348736 hasPublicationYear "2003" @default.
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