FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W78381853> ?p ?o ?g. }

• W78381853 endingPage "668" @default.
• W78381853 startingPage "661" @default.
• W78381853 abstract "Control properties of the gluconeogenic pathway in hepatocytes isolated from starved rats were studied in the presence of glucose. The following observations were made. (1) Glucose stimulated the rate of glucose production from 20 mM-glycerol, from a mixture of 20 mM-lactate and 2 mM-pyruvate, or from pyruvate alone; no stimulation was observed with 20 mM-alanine or 20 mM-dihydroxyacetone. Maximal stimulation was obtained between 2 and 5 mM-glucose, depending on the conditions. At concentrations above 6 mM, gluconeogenesis declined again, so that at 10 mM-glucose the glucose production rate became equal to that in its absence. (2) With glycerol, stimulation of gluconeogenesis by glucose was accompanied by oxidation of cytosolic NADH and reduction of mitochondrial NAD+ and was insensitive to the transaminase inhibitor amino-oxyacetate; this indicated that glucose accelerated the rate of transport of cytosolic reducing equivalents to the mitochondria via the glycerol 1-phosphate shuttle. (3) With lactate plus pyruvate (10:1) as substrates, stimulation of gluconeogenesis by glucose was almost additive to that obtained with glucagon. From an analysis of the effect of glucose on the curves relating gluconeogenic flux and the steady-state intracellular concentrations of gluconeogenic intermediates under various conditions, in the absence and presence of glucagon, it was concluded that addition of glucose stimulated both phosphoenolpyruvate carboxykinase and pyruvate carboxylase activity." @default.
• W78381853 created "2016-06-24" @default.
• W78381853 creator A5021349434 @default.
• W78381853 creator A5052175160 @default.
• W78381853 creator A5070427151 @default.
• W78381853 creator A5081440804 @default.
• W78381853 date "1987-08-01" @default.
• W78381853 modified "2023-10-14" @default.
• W78381853 title "Stimulation by glucose of gluconeogenesis in hepatocytes isolated from starved rats" @default.
• W78381853 cites W1482090517 @default.
• W78381853 cites W1495556880 @default.
• W78381853 cites W1524136845 @default.
• W78381853 cites W1538807883 @default.
• W78381853 cites W1541460729 @default.
• W78381853 cites W1548454840 @default.
• W78381853 cites W1554141820 @default.
• W78381853 cites W1588593248 @default.
• W78381853 cites W1606168019 @default.
• W78381853 cites W173391054 @default.
• W78381853 cites W1747247635 @default.
• W78381853 cites W1801184284 @default.
• W78381853 cites W1839389740 @default.
• W78381853 cites W1877568403 @default.
• W78381853 cites W1910312098 @default.
• W78381853 cites W1917157275 @default.
• W78381853 cites W193452758 @default.
• W78381853 cites W1955616937 @default.
• W78381853 cites W1976784930 @default.
• W78381853 cites W1981645572 @default.
• W78381853 cites W2006790549 @default.
• W78381853 cites W2008946840 @default.
• W78381853 cites W2029993834 @default.
• W78381853 cites W2032108649 @default.
• W78381853 cites W2056865735 @default.
• W78381853 cites W2060862675 @default.
• W78381853 cites W2069287015 @default.
• W78381853 cites W2072482644 @default.
• W78381853 cites W2075422086 @default.
• W78381853 cites W2077308294 @default.
• W78381853 cites W2083260212 @default.
• W78381853 cites W2083414088 @default.
• W78381853 cites W2086130857 @default.
• W78381853 cites W2134883783 @default.
• W78381853 cites W2158334465 @default.
• W78381853 cites W2300522002 @default.
• W78381853 cites W2345794510 @default.
• W78381853 cites W276326461 @default.
• W78381853 cites W2975437157 @default.
• W78381853 cites W4545634 @default.
• W78381853 cites W50858897 @default.
• W78381853 doi "https://doi.org/10.1042/bj2450661" @default.
• W78381853 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1148183" @default.
• W78381853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3663184" @default.
• W78381853 hasPublicationYear "1987" @default.
• W78381853 type Work @default.
• W78381853 sameAs 78381853 @default.
• W78381853 citedByCount "23" @default.
• W78381853 countsByYear W783818532012 @default.
• W78381853 countsByYear W783818532013 @default.
• W78381853 countsByYear W783818532021 @default.
• W78381853 crossrefType "journal-article" @default.
• W78381853 hasAuthorship W78381853A5021349434 @default.
• W78381853 hasAuthorship W78381853A5052175160 @default.
• W78381853 hasAuthorship W78381853A5070427151 @default.
• W78381853 hasAuthorship W78381853A5081440804 @default.
• W78381853 hasBestOaLocation W783818532 @default.
• W78381853 hasConcept C126322002 @default.
• W78381853 hasConcept C134018914 @default.
• W78381853 hasConcept C140137476 @default.
• W78381853 hasConcept C143937172 @default.
• W78381853 hasConcept C181199279 @default.
• W78381853 hasConcept C185592680 @default.
• W78381853 hasConcept C20904676 @default.
• W78381853 hasConcept C24998067 @default.
• W78381853 hasConcept C2778563252 @default.
• W78381853 hasConcept C2779306644 @default.
• W78381853 hasConcept C2779735320 @default.
• W78381853 hasConcept C2780881558 @default.
• W78381853 hasConcept C55493867 @default.
• W78381853 hasConcept C62231903 @default.
• W78381853 hasConcept C71924100 @default.
• W78381853 hasConcept C86803240 @default.
• W78381853 hasConceptScore W78381853C126322002 @default.
• W78381853 hasConceptScore W78381853C134018914 @default.
• W78381853 hasConceptScore W78381853C140137476 @default.
• W78381853 hasConceptScore W78381853C143937172 @default.
• W78381853 hasConceptScore W78381853C181199279 @default.
• W78381853 hasConceptScore W78381853C185592680 @default.
• W78381853 hasConceptScore W78381853C20904676 @default.
• W78381853 hasConceptScore W78381853C24998067 @default.
• W78381853 hasConceptScore W78381853C2778563252 @default.
• W78381853 hasConceptScore W78381853C2779306644 @default.
• W78381853 hasConceptScore W78381853C2779735320 @default.
• W78381853 hasConceptScore W78381853C2780881558 @default.
• W78381853 hasConceptScore W78381853C55493867 @default.
• W78381853 hasConceptScore W78381853C62231903 @default.
• W78381853 hasConceptScore W78381853C71924100 @default.
• W78381853 hasConceptScore W78381853C86803240 @default.

• next