FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W78487540> ?p ?o ?g. }

• W78487540 endingPage "220" @default.
• W78487540 startingPage "212" @default.
• W78487540 abstract "This chapter provides an overview on antigen. There are two principal views of what happens during antigen presentation: the majority view and the minority view. According to the majority view, antigen presentation is divided arbitrarily into eight steps. The antigen enters the antigen-presenting cell by phagocytosis if it is large or by pinocytosis if it is small. The antigen-containing phagocytic or pinocytic vesicle pinches off from the membrane. The vesicle fuses with one or more lysosomes. Most of the antigenic protein is degraded into small fragments by acidic proteases, but some larger peptides remain undegraded. Some of the larger peptides associate physically with the major histocompatibility complex (MHC) molecules. Lysosomes containing the degradation products of the antigen empty their contents to the cell's exterior by exocytosis. MHC molecules with antigen fragments that are bound to them reach the cell surface by the same process. On the cell surface, the MHC-associated antigen fragments are recognized by the specific T cell receptor (TCR) of an appropriate T lymphocyte. According to the minority view, antigen presentation consists of only three steps: (1) the antigen binds to certain molecules on the APC surface, (2) via currents in the membrane, the molecule with the antigen bound to it is brought close to the MHC molecule and the constellation of the MHC molecule and of the antigen located nearby is recognized by the TCR. The chapter discusses that it is not possible to check all the evidence that has been put forward in favour of one or the other of the two hypotheses." @default.
• W78487540 created "2016-06-24" @default.
• W78487540 creator A5047528427 @default.
• W78487540 creator A5050072303 @default.
• W78487540 date "1986-01-01" @default.
• W78487540 modified "2023-09-23" @default.
• W78487540 title "Antigen Presentation: Paradigm Lost?" @default.
• W78487540 cites W1500768060 @default.
• W78487540 cites W1502867146 @default.
• W78487540 cites W1553353028 @default.
• W78487540 cites W1603151752 @default.
• W78487540 cites W1626808193 @default.
• W78487540 cites W1650967815 @default.
• W78487540 cites W1658359452 @default.
• W78487540 cites W1966564265 @default.
• W78487540 cites W1967543093 @default.
• W78487540 cites W1973171778 @default.
• W78487540 cites W1981154516 @default.
• W78487540 cites W1988103710 @default.
• W78487540 cites W1992577200 @default.
• W78487540 cites W1997796433 @default.
• W78487540 cites W2009441693 @default.
• W78487540 cites W2017428346 @default.
• W78487540 cites W2027925670 @default.
• W78487540 cites W2032848978 @default.
• W78487540 cites W2043856037 @default.
• W78487540 cites W2048731569 @default.
• W78487540 cites W2049706113 @default.
• W78487540 cites W2052724248 @default.
• W78487540 cites W2057956380 @default.
• W78487540 cites W2062086594 @default.
• W78487540 cites W2072649760 @default.
• W78487540 cites W2078413531 @default.
• W78487540 cites W2086651259 @default.
• W78487540 cites W2087969980 @default.
• W78487540 cites W2088084755 @default.
• W78487540 cites W2094482300 @default.
• W78487540 cites W2094805401 @default.
• W78487540 cites W2096273252 @default.
• W78487540 cites W2096747204 @default.
• W78487540 cites W2102113761 @default.
• W78487540 cites W2102151654 @default.
• W78487540 cites W2116762798 @default.
• W78487540 cites W2125841464 @default.
• W78487540 cites W2138948114 @default.
• W78487540 cites W2152280976 @default.
• W78487540 cites W2155237167 @default.
• W78487540 cites W2167948410 @default.
• W78487540 cites W2405335272 @default.
• W78487540 cites W4231565477 @default.
• W78487540 cites W4313310126 @default.
• W78487540 doi "https://doi.org/10.1016/b978-0-12-174685-8.50025-1" @default.
• W78487540 hasPublicationYear "1986" @default.
• W78487540 type Work @default.
• W78487540 sameAs 78487540 @default.
• W78487540 citedByCount "4" @default.
• W78487540 crossrefType "book-chapter" @default.
• W78487540 hasAuthorship W78487540A5047528427 @default.
• W78487540 hasAuthorship W78487540A5050072303 @default.
• W78487540 hasConcept C108249834 @default.
• W78487540 hasConcept C147483822 @default.
• W78487540 hasConcept C1491633281 @default.
• W78487540 hasConcept C170627219 @default.
• W78487540 hasConcept C185592680 @default.
• W78487540 hasConcept C19317047 @default.
• W78487540 hasConcept C197695756 @default.
• W78487540 hasConcept C203014093 @default.
• W78487540 hasConcept C207936829 @default.
• W78487540 hasConcept C2776090121 @default.
• W78487540 hasConcept C28005876 @default.
• W78487540 hasConcept C40017333 @default.
• W78487540 hasConcept C55493867 @default.
• W78487540 hasConcept C67662055 @default.
• W78487540 hasConcept C83464605 @default.
• W78487540 hasConcept C86803240 @default.
• W78487540 hasConcept C8891405 @default.
• W78487540 hasConcept C95444343 @default.
• W78487540 hasConceptScore W78487540C108249834 @default.
• W78487540 hasConceptScore W78487540C147483822 @default.
• W78487540 hasConceptScore W78487540C1491633281 @default.
• W78487540 hasConceptScore W78487540C170627219 @default.
• W78487540 hasConceptScore W78487540C185592680 @default.
• W78487540 hasConceptScore W78487540C19317047 @default.
• W78487540 hasConceptScore W78487540C197695756 @default.
• W78487540 hasConceptScore W78487540C203014093 @default.
• W78487540 hasConceptScore W78487540C207936829 @default.
• W78487540 hasConceptScore W78487540C2776090121 @default.
• W78487540 hasConceptScore W78487540C28005876 @default.
• W78487540 hasConceptScore W78487540C40017333 @default.
• W78487540 hasConceptScore W78487540C55493867 @default.
• W78487540 hasConceptScore W78487540C67662055 @default.
• W78487540 hasConceptScore W78487540C83464605 @default.
• W78487540 hasConceptScore W78487540C86803240 @default.
• W78487540 hasConceptScore W78487540C8891405 @default.
• W78487540 hasConceptScore W78487540C95444343 @default.
• W78487540 hasLocation W784875401 @default.
• W78487540 hasOpenAccess W78487540 @default.
• W78487540 hasPrimaryLocation W784875401 @default.

• next