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- W788216640 abstract "In acute organic pain the nervous system is intact and the pain is mediated by the normal physiolocigal processes of nociception (Fig. 1). In chronic pain of usual organic type, the nervous system should be morphologically intact except for changes that hypothetically may occur peripherally in the form of nerve sprouts into tumours or proliferative tissue in spondylosis and arthrosis. Such sprouts might have a nociceptive function and be very sensitive in analogy with nerve sprouts in a neuroma. Among the mechanisms of chronic pain we have also to consider the possibility that a longlasting barrage of nociceptive impulses may create a central neuronal dysfunction. It may be assumed that such functional changes can outlast the period of afferent activity originating in the diseased organ and act as autonomous pain-producing foci after the peripheral lesion has healed." @default.
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- W788216640 date "1980-01-01" @default.
- W788216640 modified "2023-09-27" @default.
- W788216640 title "Mechanisms of Neurologic Pain and Measurements of Sensibility" @default.
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- W788216640 doi "https://doi.org/10.1007/978-3-642-47091-2_396" @default.
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