Matches in SemOpenAlex for { <https://semopenalex.org/work/W788233899> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W788233899 abstract "Stem cell research, especially the one dealing with human embryonic stem cells, is a major topic nowadays. In the last few years studies about human embryonic stem cell derived cardiomyocytes highlighted the importance of those, as their characteristics are almost identical as of the cardiomyocytes in the heart (i.e. the contraction of those cells). The studies concentrate on the ability of using cardiomyocytes in the drug development for cardiac diseases or in regenerative medicine and cell replacement therapies. In contrast some researchers concentrate on microRNAs (miRNAs) as regulators in the development of cardiomyocytes. This study combines both research topics as it deals with stem cells and miRNAs (as well as their target mRNAs). A main objective is to find differentially expressed genes by using Significance Analysis of Microarrays (SAM) as method. Furthermore miRNA target prediction is applied and the identified targets are compared with the ones found by SAM. With an intersection approach we derived 41 targets of up-regulated miRNAs and 25 targets of down-regulated miRNAs, which can be the basis for further studies (i.e. knock-out experiments)." @default.
- W788233899 created "2016-06-24" @default.
- W788233899 creator A5054382941 @default.
- W788233899 date "2011-01-01" @default.
- W788233899 modified "2023-09-23" @default.
- W788233899 title "Identification of miRNAs and their target genes in stem cell derived cardiomyocytes" @default.
- W788233899 hasPublicationYear "2011" @default.
- W788233899 type Work @default.
- W788233899 sameAs 788233899 @default.
- W788233899 citedByCount "0" @default.
- W788233899 crossrefType "journal-article" @default.
- W788233899 hasAuthorship W788233899A5054382941 @default.
- W788233899 hasConcept C104317684 @default.
- W788233899 hasConcept C10854531 @default.
- W788233899 hasConcept C145059251 @default.
- W788233899 hasConcept C145103041 @default.
- W788233899 hasConcept C1491633281 @default.
- W788233899 hasConcept C150194340 @default.
- W788233899 hasConcept C28328180 @default.
- W788233899 hasConcept C54355233 @default.
- W788233899 hasConcept C60644358 @default.
- W788233899 hasConcept C70721500 @default.
- W788233899 hasConcept C86803240 @default.
- W788233899 hasConcept C95371953 @default.
- W788233899 hasConcept C95444343 @default.
- W788233899 hasConceptScore W788233899C104317684 @default.
- W788233899 hasConceptScore W788233899C10854531 @default.
- W788233899 hasConceptScore W788233899C145059251 @default.
- W788233899 hasConceptScore W788233899C145103041 @default.
- W788233899 hasConceptScore W788233899C1491633281 @default.
- W788233899 hasConceptScore W788233899C150194340 @default.
- W788233899 hasConceptScore W788233899C28328180 @default.
- W788233899 hasConceptScore W788233899C54355233 @default.
- W788233899 hasConceptScore W788233899C60644358 @default.
- W788233899 hasConceptScore W788233899C70721500 @default.
- W788233899 hasConceptScore W788233899C86803240 @default.
- W788233899 hasConceptScore W788233899C95371953 @default.
- W788233899 hasConceptScore W788233899C95444343 @default.
- W788233899 hasLocation W7882338991 @default.
- W788233899 hasOpenAccess W788233899 @default.
- W788233899 hasPrimaryLocation W7882338991 @default.
- W788233899 hasRelatedWork W193496030 @default.
- W788233899 hasRelatedWork W1994437038 @default.
- W788233899 hasRelatedWork W1994900589 @default.
- W788233899 hasRelatedWork W2039432662 @default.
- W788233899 hasRelatedWork W2048452977 @default.
- W788233899 hasRelatedWork W2106095453 @default.
- W788233899 hasRelatedWork W2116325869 @default.
- W788233899 hasRelatedWork W2118281944 @default.
- W788233899 hasRelatedWork W2129007306 @default.
- W788233899 hasRelatedWork W2145286636 @default.
- W788233899 hasRelatedWork W2164253690 @default.
- W788233899 hasRelatedWork W2359339849 @default.
- W788233899 hasRelatedWork W2402571281 @default.
- W788233899 hasRelatedWork W2437623589 @default.
- W788233899 hasRelatedWork W2586074121 @default.
- W788233899 hasRelatedWork W2801103595 @default.
- W788233899 hasRelatedWork W2912917840 @default.
- W788233899 hasRelatedWork W2978314058 @default.
- W788233899 hasRelatedWork W3041169941 @default.
- W788233899 hasRelatedWork W2185256441 @default.
- W788233899 isParatext "false" @default.
- W788233899 isRetracted "false" @default.
- W788233899 magId "788233899" @default.
- W788233899 workType "article" @default.