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- W788272009 abstract "The cellular biological function of the ubiquitin-proteasome pathway as a major intracellular protein degradation pathway, and as an important modulator for the regulation of many fundamental cellular processes has been greatly appreciated over the last decade. The critical role of the ubiquitin-proteasome pathway in viral pathogenesis has become increasingly apparent. Many viruses have been reported to evolve different strategies to utilize the ubiquitin-proteasome pathway for their own benefits. Here, we review the general background and function of the ubiquitin-proteasome pathway, summarize our current understanding of how viruses use this pathway to target cellular proteins, and finally, discuss the roles of this pathway in enteroviral infection, and the potential therapeutic application of proteasome inhibition in myocarditis." @default.
- W788272009 created "2016-06-24" @default.
- W788272009 creator A5013180607 @default.
- W788272009 creator A5087430520 @default.
- W788272009 date "2006-01-01" @default.
- W788272009 modified "2023-10-06" @default.
- W788272009 title "The ubiquitin–proteasome pathway in viral infectionsThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum." @default.
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- W788272009 doi "https://doi.org/10.1139/y05-144" @default.
- W788272009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16845885" @default.
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