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• W788505253 abstract "Myeloid differentiation factor 88 (MyD88) is a pivotal adaptor in the TLR/IL-1R signaling pathway, which plays an important role in activating the innate immune system. Although MyD88 genes have been identified in a variety of species, they have not been systematically characterized in scallops. In this study, five MyD88 genes were identified in Yesso scallop (Patinopecten yessoensis), PyMyD88-1, PyMyD88-2a, PyMyD88-2b, PyMyD88-3 and PyMyD88-4, which consisted of two pairs of tandem duplications located on the same chromosome. To our knowledge, this is the largest number of MyD88 genes found in an invertebrate. Phylogenetic and protein structural analyses were carried out to determine the identities and evolutionary relationships of these genes. PyMyD88s have highly conserved structures compared to MyD88 genes from other invertebrate species, except for PyMyD88-4, which contains only a DD domain, suggesting the evolutionarily conserved form of this particular gene member. We investigated the expression profiles of PyMyD88 genes at different developmental stages and in healthy adult tissues and hemocytes after Micrococcus luteus and Vibrio anguillarum infection using quantitative real-time PCR (qRT-PCR). The expression of most PyMyD88s was significantly induced in the acute phase (3–6 h) after infection with both gram-positive (M. luteus) and gram-negative (V. anguillarum) bacteria, with much more dramatic changes in PyMyD88 expression being observed after V. anguillarum challenge. Collectively, the abundance of MyD88s and their specific expression patterns provide insight into their versatile roles in the response of the bivalve innate immune system to gram-negative bacterial pathogens." @default.
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• W788505253 date "2015-10-01" @default.
• W788505253 modified "2023-10-16" @default.
• W788505253 title "Genome-wide identification and characterization of five MyD88 duplication genes in Yesso scallop (Patinopecten yessoensis) and expression changes in response to bacterial challenge" @default.
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• W788505253 cites W1930598094 @default.
• W788505253 cites W1965971815 @default.
• W788505253 cites W1966747379 @default.
• W788505253 cites W1967824654 @default.
• W788505253 cites W1969501356 @default.
• W788505253 cites W1971010512 @default.
• W788505253 cites W1973405021 @default.
• W788505253 cites W1981014132 @default.
• W788505253 cites W1982216579 @default.
• W788505253 cites W1994060026 @default.
• W788505253 cites W1995744610 @default.
• W788505253 cites W1995877471 @default.
• W788505253 cites W1996767422 @default.
• W788505253 cites W1998585620 @default.
• W788505253 cites W2001554554 @default.
• W788505253 cites W2004465286 @default.
• W788505253 cites W2004739382 @default.
• W788505253 cites W2010472128 @default.
• W788505253 cites W2013313638 @default.
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• W788505253 cites W2049718338 @default.
• W788505253 cites W2060029228 @default.
• W788505253 cites W2067597532 @default.
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• W788505253 cites W2075457789 @default.
• W788505253 cites W2077072873 @default.
• W788505253 cites W2077206825 @default.
• W788505253 cites W2083829960 @default.
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• W788505253 doi "https://doi.org/10.1016/j.fsi.2015.06.028" @default.
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