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- W79130015 abstract "Early and effective reperfusion is the primary treatment goal in acute myocardial infarction. The use of fibrinolytic (lytic) therapy to achieve early infarct vessel patency is well established and recommended where primary percutaneous coronary intervention (PCI) is not available. Several lytic agents are available with differing advantages and disadvantages. Contraindications to lytic therapy are important to appreciate as the major complication, intracranial hemorrhage, is potentially devastating. Rescue angioplasty is necessary if reperfusion is not achieved by lytic therapy. After lytic therapy, early transfer to a PCI-capable facility for angiography may be beneficial in high-risk patients regardless of reperfusion status. The routine use of lytics with planned primary PCI is not recommended, however, as adverse outcomes may result. A strategy of facilitated PCI with half-dose lytics and GP IIb/IIIa is also currently not recommended." @default.
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- W79130015 date "2009-08-31" @default.
- W79130015 modified "2023-10-16" @default.
- W79130015 title "Fibrinolysis and Facilitated PCI" @default.
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- W79130015 doi "https://doi.org/10.1007/978-1-60327-235-3_13" @default.
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