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- W79221777 abstract "This chapter describes the nature and function of specific H-linked immune response genes and immune suppression genes. The activities of histocompatibility (H)-linked Ir genes have become a problem of increasing interest for immunologists, particularly as the mapping of these genes has been localized to a chromosomal region, the I region, which also controls other important traits such as cell interaction in the regulation of immune responses, mixed lymphocyte, and graft-versus-host responses and expression of a new class of alloantigens, Ia antigens, on the surface of B cells, T cells, and macrophages. The increasing awareness of the role of these genes in the control of responsiveness to thymus-dependent antigens and the demonstration from several laboratories of the production of factors from activated T cells possessing determinants coded for in the same I region have further emphasized the importance of understanding the function of Ir genes and their products." @default.
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- W79221777 date "1976-01-01" @default.
- W79221777 modified "2023-10-18" @default.
- W79221777 title "THE NATURE AND FUNCTION OF SPECIFIC H-LINKED IMMUNE RESPONSE GENES AND IMMUNE SUPPRESSION GENES" @default.
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- W79221777 doi "https://doi.org/10.1016/b978-0-12-401660-6.50024-2" @default.
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