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- W794922832 abstract "Nine new alkaloids of the koumine (1-4), humantenine (5-7), and yohimbane (8, 9) types as well as 12 known analogues were isolated from the leaves and vine stems of Gelsemium elegans. Compound 1 is the first N-4-demethyl alkaloid of the koumine type, compound 7 is the first nor-humantenine alkaloid, and compounds 8 and 9 are the first N-1-oxide and the first seco-E-ring alkaloids, respectively, of the yohimbane type. Compounds 1 and 7 exhibited moderate cytotoxicity against five human tumor cell lines with IC50 values in the range 4.6-9.3 μM." @default.
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- W794922832 date "2015-06-23" @default.
- W794922832 modified "2023-10-10" @default.
- W794922832 title "Koumine, Humantenine, and Yohimbane Alkaloids from <i>Gelsemium elegans</i>" @default.
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- W794922832 doi "https://doi.org/10.1021/np5009619" @default.
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