Matches in SemOpenAlex for { <https://semopenalex.org/work/W795131796> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W795131796 endingPage "223" @default.
- W795131796 startingPage "193" @default.
- W795131796 abstract "INTRODUCTION The in vitro reconstitution of the bacterial 30S ribosomal subunit (Traub and Nomura 1968) followed by that of the 50S subunit (Nomura and Erdmann 1970; Fahnestock, Erdmann and Nomura 1973) has established that the information required for the assembly of this complex organelle is entirely contained in the structures of the RNA and protein components. The mechanism involved in this complex self-assembly process is now being elucidated, especially with respect to 30S ribosome assembly, by a variety of in vitro experiments. The in vitro assembly reaction, while differing in some details from in vivo assembly, very likely reflects the in vivo process in important ways. In addition, reconstitution techniques have facilitated the study of ribosome structure and structure-function relationships. A detailed review on the in vitro reconstitution of 50S subunits (Fahnestock, Held and Nomura 1972), as well as reviews on ribosome assembly in general (Nomura 1970Nomura 1973) have appeared previously. In this article, we summarize and discuss the work related to ribosome assembly, concentrating mainly on the 30S subunit, including several recent developments in this area. PARTIAL RECONSTITUTION OF RIBOSOMES The first step in the analysis of the functional role of ribosomal components was the development of a system for reconstituting ribosomes that had been partially disassembled (Staehelin and Meselson 1966; Hosokawa, Fujimura and Nomura 1966), Selective removal of a portion of the ribosomal protein (“split proteins”) was accomplished by centrifugation of the ribosomes in 5 M CsCl in the presence of 0.04 M Mg ++ . The functionally inactive nucleoprotein..." @default.
- W795131796 created "2016-06-24" @default.
- W795131796 creator A5051024347 @default.
- W795131796 creator A5072834548 @default.
- W795131796 date "1974-01-01" @default.
- W795131796 modified "2023-09-23" @default.
- W795131796 title "Reconstitution of Ribosomes: Studies of Ribosome Structure, Function and Assembly" @default.
- W795131796 doi "https://doi.org/10.1101/087969110.4.193" @default.
- W795131796 hasPublicationYear "1974" @default.
- W795131796 type Work @default.
- W795131796 sameAs 795131796 @default.
- W795131796 citedByCount "18" @default.
- W795131796 countsByYear W7951317962021 @default.
- W795131796 crossrefType "journal-article" @default.
- W795131796 hasAuthorship W795131796A5051024347 @default.
- W795131796 hasAuthorship W795131796A5072834548 @default.
- W795131796 hasConcept C104292427 @default.
- W795131796 hasConcept C104317684 @default.
- W795131796 hasConcept C107824862 @default.
- W795131796 hasConcept C12554922 @default.
- W795131796 hasConcept C129194359 @default.
- W795131796 hasConcept C168240541 @default.
- W795131796 hasConcept C202751555 @default.
- W795131796 hasConcept C301363 @default.
- W795131796 hasConcept C3675279 @default.
- W795131796 hasConcept C38062823 @default.
- W795131796 hasConcept C52721335 @default.
- W795131796 hasConcept C552990157 @default.
- W795131796 hasConcept C55493867 @default.
- W795131796 hasConcept C60325843 @default.
- W795131796 hasConcept C67705224 @default.
- W795131796 hasConcept C67905577 @default.
- W795131796 hasConcept C69080955 @default.
- W795131796 hasConcept C86803240 @default.
- W795131796 hasConcept C88478588 @default.
- W795131796 hasConcept C95444343 @default.
- W795131796 hasConcept C96267730 @default.
- W795131796 hasConceptScore W795131796C104292427 @default.
- W795131796 hasConceptScore W795131796C104317684 @default.
- W795131796 hasConceptScore W795131796C107824862 @default.
- W795131796 hasConceptScore W795131796C12554922 @default.
- W795131796 hasConceptScore W795131796C129194359 @default.
- W795131796 hasConceptScore W795131796C168240541 @default.
- W795131796 hasConceptScore W795131796C202751555 @default.
- W795131796 hasConceptScore W795131796C301363 @default.
- W795131796 hasConceptScore W795131796C3675279 @default.
- W795131796 hasConceptScore W795131796C38062823 @default.
- W795131796 hasConceptScore W795131796C52721335 @default.
- W795131796 hasConceptScore W795131796C552990157 @default.
- W795131796 hasConceptScore W795131796C55493867 @default.
- W795131796 hasConceptScore W795131796C60325843 @default.
- W795131796 hasConceptScore W795131796C67705224 @default.
- W795131796 hasConceptScore W795131796C67905577 @default.
- W795131796 hasConceptScore W795131796C69080955 @default.
- W795131796 hasConceptScore W795131796C86803240 @default.
- W795131796 hasConceptScore W795131796C88478588 @default.
- W795131796 hasConceptScore W795131796C95444343 @default.
- W795131796 hasConceptScore W795131796C96267730 @default.
- W795131796 hasLocation W7951317961 @default.
- W795131796 hasOpenAccess W795131796 @default.
- W795131796 hasPrimaryLocation W7951317961 @default.
- W795131796 hasRelatedWork W1040338230 @default.
- W795131796 hasRelatedWork W1489561579 @default.
- W795131796 hasRelatedWork W1492288245 @default.
- W795131796 hasRelatedWork W1511716478 @default.
- W795131796 hasRelatedWork W1596239314 @default.
- W795131796 hasRelatedWork W1965589383 @default.
- W795131796 hasRelatedWork W1995133838 @default.
- W795131796 hasRelatedWork W2031721211 @default.
- W795131796 hasRelatedWork W2032042692 @default.
- W795131796 hasRelatedWork W2040209327 @default.
- W795131796 hasRelatedWork W2068980328 @default.
- W795131796 hasRelatedWork W2102992442 @default.
- W795131796 hasRelatedWork W2110519885 @default.
- W795131796 hasRelatedWork W2129576051 @default.
- W795131796 hasRelatedWork W2142055951 @default.
- W795131796 hasRelatedWork W2755767741 @default.
- W795131796 hasRelatedWork W2806245693 @default.
- W795131796 hasRelatedWork W2887269027 @default.
- W795131796 hasRelatedWork W3213401265 @default.
- W795131796 hasRelatedWork W2169118529 @default.
- W795131796 hasVolume "04" @default.
- W795131796 isParatext "false" @default.
- W795131796 isRetracted "false" @default.
- W795131796 magId "795131796" @default.
- W795131796 workType "article" @default.