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- W796611340 abstract "In this work we have investigated plants used in folk medicine in the form of infusion. As a part of our project, we studied species used for the treatment of gastric ulcers: Quassia amara (Simaroubaceae), Alchornea castaneifolia (Euphorbiaceae), Curatella americana (Dilleniaceae) and Hancornea speciosa (Apocynaceae). The extracts were submitted to pharmacological evaluation in different models to evaluate their antiulcer activities. The active extracts were fractionated by chromatographic techniques and the substances were identified by spectrometric methods. Quassia amara afforded mainly steroids and quassinoids; C. americana gave tannins, catequins, terpenes and phenolic acids; A. castaneifolia afforded glycosilated flavonoids and H. speciosa gave chlorogenic acid and catechin. These substances supported the antiulcer properties found in the investigated extracts. Other species commonly found in Brazil as infusions are Ilex amara and Ilex theezans (Aquifoleaceae), both considered as aduterant of Ilex paraguariensis, the traditional mate. The analyses of Ilex theezans afforded triterpenes, saponins and a new sulphated arbutin derivative, whereas Ilex amara gave one flavonoids and eleven triterpene saponins, two of them are new derivatives. Saponins of I. amara were used to establish chemical differenciation between true and false mates by HPLC-DAD analysis. The HPLCNMR and HPLC-MS techniques were used to determine the flavonoidic composition of aqueous extract of Sorocea bomplandii (Moraceae), an adulterant of espinheira-santa (Maytenus ilicifolia – Celastraceae). This approach allowed to identify the flavonoids present in minor amounts in the infusion and allowed to differenciate between true and false espinheiras-santas. Fabio Donisete Pezzuto de Andrade –Tese de Doutorado 5" @default.
- W796611340 created "2016-06-24" @default.
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- W796611340 date "2003-01-01" @default.
- W796611340 modified "2023-09-22" @default.
- W796611340 title "Estudo químico de chás brasileiros" @default.
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