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- W79775631 abstract "Rhabdomyosarcoma (RMS) is a complex, highly malignant tumor of children and adolescents that arises from embryonal mesenchyme with the potential of differentiating to skeletal muscle. Presenting deceptively as a small lump under the skin or in a more occult location, this tumor grows persistently by local extension and metastasizes by lymph nodes and blood stream to more distant sites. During the past 20 years, a multidisciplinary approach has been promoted that has led to accurate histopathologic testing, staging, and multimodality therapy with surgery, radiotherapy, and chemotherapy to control local and metastatic disease. Many investigators have contributed to this progress, which has resulted in a dramatic increase in the overall survival rate to 55 per cent for the entire group of 686 patients on the IRS-I study." @default.
- W79775631 created "2016-06-24" @default.
- W79775631 creator A5062591516 @default.
- W79775631 date "1987-12-01" @default.
- W79775631 modified "2023-10-16" @default.
- W79775631 title "Rhabdomyosarcoma in Children and Adolescents: A Review" @default.
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- W79775631 doi "https://doi.org/10.1016/s0889-8588(18)30644-0" @default.
- W79775631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3323176" @default.
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