Matches in SemOpenAlex for { <https://semopenalex.org/work/W7981867> ?p ?o ?g. }
- W7981867 endingPage "590" @default.
- W7981867 startingPage "567" @default.
- W7981867 abstract "Although iron is essential for the proper functioning of all living cells, it is toxic when present in excess. In the presence of molecular oxygen, “loosely bound” iron is able to redox cycle between the two most stable oxidation states, iron(II) and iron(III), thereby generating oxygen-derived free radicals, such as the hydroxyl radical [1]. Hydroxyl radicals are highly reactive and capable of interacting with most types of biological molecules, including sugars, lipids, proteins and nucleic acids, resulting in peroxidative tissue damage [2]. The uncontrolled production of such highly reactive species is undesirable, and thus, a number of protective strategies are adopted by cells to prevent their formation. One of the most important is the tight control of iron storage, transport and distribution. In fact, iron metabolism in man is highly conservative with the majority of iron being recycled within the body. Since man lacks a physiological mechanism for eliminating iron, iron homeostasis is largely achieved by the regulation of iron absorption. In addition, the levels of many of the proteins involved in iron transport, storage and catalysis are controlled by body iron levels." @default.
- W7981867 created "2016-06-24" @default.
- W7981867 creator A5005319784 @default.
- W7981867 creator A5020843793 @default.
- W7981867 date "2011-11-24" @default.
- W7981867 modified "2023-10-05" @default.
- W7981867 title "The Properties of Therapeutically Useful Iron Chelators" @default.
- W7981867 cites W1538748480 @default.
- W7981867 cites W1637392459 @default.
- W7981867 cites W1918002809 @default.
- W7981867 cites W1964317877 @default.
- W7981867 cites W1966644042 @default.
- W7981867 cites W1968403725 @default.
- W7981867 cites W1973263780 @default.
- W7981867 cites W1978758874 @default.
- W7981867 cites W1994687717 @default.
- W7981867 cites W1996308138 @default.
- W7981867 cites W1997795108 @default.
- W7981867 cites W2006250045 @default.
- W7981867 cites W2016400380 @default.
- W7981867 cites W2018768546 @default.
- W7981867 cites W2022005654 @default.
- W7981867 cites W2022708198 @default.
- W7981867 cites W2028995913 @default.
- W7981867 cites W2031036589 @default.
- W7981867 cites W2033066083 @default.
- W7981867 cites W2035599711 @default.
- W7981867 cites W2036746820 @default.
- W7981867 cites W2040901717 @default.
- W7981867 cites W2042014322 @default.
- W7981867 cites W2045300018 @default.
- W7981867 cites W2048210923 @default.
- W7981867 cites W2055981765 @default.
- W7981867 cites W2056570094 @default.
- W7981867 cites W2057426811 @default.
- W7981867 cites W2071858022 @default.
- W7981867 cites W2072537528 @default.
- W7981867 cites W2072644783 @default.
- W7981867 cites W2076446665 @default.
- W7981867 cites W2093073780 @default.
- W7981867 cites W2093328959 @default.
- W7981867 cites W2099143902 @default.
- W7981867 cites W2105949942 @default.
- W7981867 cites W2111089723 @default.
- W7981867 cites W2120041716 @default.
- W7981867 cites W2135342762 @default.
- W7981867 cites W2146033714 @default.
- W7981867 cites W2146921545 @default.
- W7981867 cites W2151127435 @default.
- W7981867 cites W2168793485 @default.
- W7981867 cites W2214504204 @default.
- W7981867 cites W26210460 @default.
- W7981867 cites W264696119 @default.
- W7981867 cites W2951227944 @default.
- W7981867 cites W30168135 @default.
- W7981867 cites W32000358 @default.
- W7981867 cites W426804056 @default.
- W7981867 cites W58235600 @default.
- W7981867 doi "https://doi.org/10.1007/978-1-60327-485-2_27" @default.
- W7981867 hasPublicationYear "2011" @default.
- W7981867 type Work @default.
- W7981867 sameAs 7981867 @default.
- W7981867 citedByCount "1" @default.
- W7981867 countsByYear W79818672018 @default.
- W7981867 crossrefType "book-chapter" @default.
- W7981867 hasAuthorship W7981867A5005319784 @default.
- W7981867 hasAuthorship W7981867A5020843793 @default.
- W7981867 hasConcept C12554922 @default.
- W7981867 hasConcept C139066938 @default.
- W7981867 hasConcept C178790620 @default.
- W7981867 hasConcept C179104552 @default.
- W7981867 hasConcept C185592680 @default.
- W7981867 hasConcept C24107716 @default.
- W7981867 hasConcept C2993864201 @default.
- W7981867 hasConcept C48349386 @default.
- W7981867 hasConcept C540031477 @default.
- W7981867 hasConcept C55493867 @default.
- W7981867 hasConcept C55904794 @default.
- W7981867 hasConcept C62231903 @default.
- W7981867 hasConcept C86803240 @default.
- W7981867 hasConceptScore W7981867C12554922 @default.
- W7981867 hasConceptScore W7981867C139066938 @default.
- W7981867 hasConceptScore W7981867C178790620 @default.
- W7981867 hasConceptScore W7981867C179104552 @default.
- W7981867 hasConceptScore W7981867C185592680 @default.
- W7981867 hasConceptScore W7981867C24107716 @default.
- W7981867 hasConceptScore W7981867C2993864201 @default.
- W7981867 hasConceptScore W7981867C48349386 @default.
- W7981867 hasConceptScore W7981867C540031477 @default.
- W7981867 hasConceptScore W7981867C55493867 @default.
- W7981867 hasConceptScore W7981867C55904794 @default.
- W7981867 hasConceptScore W7981867C62231903 @default.
- W7981867 hasConceptScore W7981867C86803240 @default.
- W7981867 hasLocation W79818671 @default.
- W7981867 hasOpenAccess W7981867 @default.
- W7981867 hasPrimaryLocation W79818671 @default.
- W7981867 hasRelatedWork W1496977441 @default.
- W7981867 hasRelatedWork W1543504406 @default.