Matches in SemOpenAlex for { <https://semopenalex.org/work/W799250984> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W799250984 abstract "Evaluation of long-term side effects of treatment is important due to the growing number of childhood cancer survivors. How kidney function is affected over time needs to be clarified. In the first article, we investigated 247 healthy infants and children and established upper reference limits for several proteins in urine, to be used as markers for glomerular and tubular proteinuria in children with cancer. In the second article, we investigated if simpler methods could replace glomerular filtration rate (GFR) as measured by iohexol clearance in children with cancer. Examples of these methods are: serum creatinine and cystatin C, urine albumin/creatinine and IgG/creatinine, as well as three formulae for estimating GFR through serum creatinine and height. We found good correlation between GFR and all tests, except the urine protein/creatinine ratios, but the prediction of GFR was unsatisfactory with the variation being too large. In article III, we found hyperfiltration in 33 % of children at diagnosis, especially in younger children with bone marrow involvement. This was previously not described, and may be related to an increased protein turnover in children with large tumor burden. In the fourth article, long-term renal affection in 69 children with cancer was studied for up to 7 years after end of treatment. Of proposed risk factors, ifosfamide treatment with or without cisplatin, radiation and nephrectomy affected GFR the most. In 6/69 children we found persistent changes in renal function. We conclude that renal function should be monitored long-term after end of potentially nephrotoxic cancer treatment." @default.
- W799250984 created "2016-06-24" @default.
- W799250984 creator A5057281435 @default.
- W799250984 date "2003-01-01" @default.
- W799250984 modified "2023-09-25" @default.
- W799250984 title "A Study of Renal Function in Children with Cancer" @default.
- W799250984 hasPublicationYear "2003" @default.
- W799250984 type Work @default.
- W799250984 sameAs 799250984 @default.
- W799250984 citedByCount "0" @default.
- W799250984 crossrefType "dissertation" @default.
- W799250984 hasAuthorship W799250984A5057281435 @default.
- W799250984 hasConcept C121608353 @default.
- W799250984 hasConcept C126189478 @default.
- W799250984 hasConcept C126322002 @default.
- W799250984 hasConcept C126894567 @default.
- W799250984 hasConcept C159641895 @default.
- W799250984 hasConcept C2779548226 @default.
- W799250984 hasConcept C2779561371 @default.
- W799250984 hasConcept C2780026642 @default.
- W799250984 hasConcept C2780091579 @default.
- W799250984 hasConcept C2780227381 @default.
- W799250984 hasConcept C2780306776 @default.
- W799250984 hasConcept C71924100 @default.
- W799250984 hasConceptScore W799250984C121608353 @default.
- W799250984 hasConceptScore W799250984C126189478 @default.
- W799250984 hasConceptScore W799250984C126322002 @default.
- W799250984 hasConceptScore W799250984C126894567 @default.
- W799250984 hasConceptScore W799250984C159641895 @default.
- W799250984 hasConceptScore W799250984C2779548226 @default.
- W799250984 hasConceptScore W799250984C2779561371 @default.
- W799250984 hasConceptScore W799250984C2780026642 @default.
- W799250984 hasConceptScore W799250984C2780091579 @default.
- W799250984 hasConceptScore W799250984C2780227381 @default.
- W799250984 hasConceptScore W799250984C2780306776 @default.
- W799250984 hasConceptScore W799250984C71924100 @default.
- W799250984 hasLocation W7992509841 @default.
- W799250984 hasOpenAccess W799250984 @default.
- W799250984 hasPrimaryLocation W7992509841 @default.
- W799250984 hasRelatedWork W148853757 @default.
- W799250984 hasRelatedWork W1940193323 @default.
- W799250984 hasRelatedWork W1967763588 @default.
- W799250984 hasRelatedWork W1994260922 @default.
- W799250984 hasRelatedWork W2002986024 @default.
- W799250984 hasRelatedWork W2005438826 @default.
- W799250984 hasRelatedWork W2011894065 @default.
- W799250984 hasRelatedWork W2025685905 @default.
- W799250984 hasRelatedWork W2031729072 @default.
- W799250984 hasRelatedWork W2052057323 @default.
- W799250984 hasRelatedWork W2054038916 @default.
- W799250984 hasRelatedWork W2057561566 @default.
- W799250984 hasRelatedWork W2057842953 @default.
- W799250984 hasRelatedWork W2107588545 @default.
- W799250984 hasRelatedWork W2157858049 @default.
- W799250984 hasRelatedWork W2197638624 @default.
- W799250984 hasRelatedWork W2238633398 @default.
- W799250984 hasRelatedWork W2364049340 @default.
- W799250984 hasRelatedWork W2404703170 @default.
- W799250984 hasRelatedWork W2418268847 @default.
- W799250984 isParatext "false" @default.
- W799250984 isRetracted "false" @default.
- W799250984 magId "799250984" @default.
- W799250984 workType "dissertation" @default.