Matches in SemOpenAlex for { <https://semopenalex.org/work/W79949186> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W79949186 startingPage "1396" @default.
- W79949186 abstract "OBJECTIVE To explore the effect of supplement energy and nourish lung (SENL) herbs on the growth of drug-resistance lung cancer cells, expression of multidrug resistance-associated protein (MRP) and mechanisms of mitochondrial and Caspase signal. METHODS Drug-resistance lung cancer cell line SW1573/2R120 was treated with SENL herbs and Adriamycin. Cellular toxicity with MTT colorimetric assay, expression of MRP protein with flow microscopy, the fluorescence intensity of mitochondria membrane potetional and Ca2+ with laser confocal microscopy, the activities of caspase-3 and caspase-8 with colorimetric assay were detected. RESULTS Compared with control group, cellular inhibitory rate was increased obviously, expression of MRP protein was decreased, mitochondria membrane potetional and intracellular Ca2+ were decreased, the activities of caspase-3 and caspase-8 were increased in the group of SENL herbs. CONCLUSION SENL herbs can interfere and reverse drug resistance in lung cancer by the mechanism of decreasing mitochondria membrane potetional and increasing the activities of caspase-3 and caspase-8." @default.
- W79949186 created "2016-06-24" @default.
- W79949186 creator A5034145724 @default.
- W79949186 creator A5060329191 @default.
- W79949186 creator A5076472783 @default.
- W79949186 date "2008-09-01" @default.
- W79949186 modified "2023-09-23" @default.
- W79949186 title "[Effect of supplement energy and nourish lung herbs on drug-resistance lung cancer with mechanisms of mitochondrial and caspase signal]." @default.
- W79949186 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19180968" @default.
- W79949186 hasPublicationYear "2008" @default.
- W79949186 type Work @default.
- W79949186 sameAs 79949186 @default.
- W79949186 citedByCount "0" @default.
- W79949186 crossrefType "journal-article" @default.
- W79949186 hasAuthorship W79949186A5034145724 @default.
- W79949186 hasAuthorship W79949186A5060329191 @default.
- W79949186 hasAuthorship W79949186A5076472783 @default.
- W79949186 hasConcept C114851261 @default.
- W79949186 hasConcept C12519072 @default.
- W79949186 hasConcept C133936738 @default.
- W79949186 hasConcept C142724271 @default.
- W79949186 hasConcept C185592680 @default.
- W79949186 hasConcept C190283241 @default.
- W79949186 hasConcept C2776256026 @default.
- W79949186 hasConcept C2780783641 @default.
- W79949186 hasConcept C28859421 @default.
- W79949186 hasConcept C31573885 @default.
- W79949186 hasConcept C502942594 @default.
- W79949186 hasConcept C55493867 @default.
- W79949186 hasConcept C71924100 @default.
- W79949186 hasConcept C79879829 @default.
- W79949186 hasConcept C86803240 @default.
- W79949186 hasConcept C89423630 @default.
- W79949186 hasConcept C95444343 @default.
- W79949186 hasConcept C98274493 @default.
- W79949186 hasConcept C98424977 @default.
- W79949186 hasConceptScore W79949186C114851261 @default.
- W79949186 hasConceptScore W79949186C12519072 @default.
- W79949186 hasConceptScore W79949186C133936738 @default.
- W79949186 hasConceptScore W79949186C142724271 @default.
- W79949186 hasConceptScore W79949186C185592680 @default.
- W79949186 hasConceptScore W79949186C190283241 @default.
- W79949186 hasConceptScore W79949186C2776256026 @default.
- W79949186 hasConceptScore W79949186C2780783641 @default.
- W79949186 hasConceptScore W79949186C28859421 @default.
- W79949186 hasConceptScore W79949186C31573885 @default.
- W79949186 hasConceptScore W79949186C502942594 @default.
- W79949186 hasConceptScore W79949186C55493867 @default.
- W79949186 hasConceptScore W79949186C71924100 @default.
- W79949186 hasConceptScore W79949186C79879829 @default.
- W79949186 hasConceptScore W79949186C86803240 @default.
- W79949186 hasConceptScore W79949186C89423630 @default.
- W79949186 hasConceptScore W79949186C95444343 @default.
- W79949186 hasConceptScore W79949186C98274493 @default.
- W79949186 hasConceptScore W79949186C98424977 @default.
- W79949186 hasIssue "9" @default.
- W79949186 hasLocation W799491861 @default.
- W79949186 hasLocation W799491862 @default.
- W79949186 hasOpenAccess W79949186 @default.
- W79949186 hasPrimaryLocation W799491861 @default.
- W79949186 hasRelatedWork W1766156668 @default.
- W79949186 hasRelatedWork W1966142860 @default.
- W79949186 hasRelatedWork W1981915038 @default.
- W79949186 hasRelatedWork W2025840674 @default.
- W79949186 hasRelatedWork W2116212750 @default.
- W79949186 hasRelatedWork W2134855813 @default.
- W79949186 hasRelatedWork W2393707749 @default.
- W79949186 hasRelatedWork W2411027382 @default.
- W79949186 hasRelatedWork W2468247319 @default.
- W79949186 hasRelatedWork W2562525096 @default.
- W79949186 hasRelatedWork W2756028785 @default.
- W79949186 hasRelatedWork W2921351876 @default.
- W79949186 hasRelatedWork W2940600165 @default.
- W79949186 hasRelatedWork W2942874185 @default.
- W79949186 hasRelatedWork W2943026183 @default.
- W79949186 hasRelatedWork W2980560484 @default.
- W79949186 hasRelatedWork W2980596307 @default.
- W79949186 hasRelatedWork W2983681627 @default.
- W79949186 hasRelatedWork W3031467782 @default.
- W79949186 hasRelatedWork W3188720930 @default.
- W79949186 hasVolume "31" @default.
- W79949186 isParatext "false" @default.
- W79949186 isRetracted "false" @default.
- W79949186 magId "79949186" @default.
- W79949186 workType "article" @default.