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- W8004490 abstract "Single-molecule function of molecular motors has been well characterized in vitro, but in vivo, motors typically function as part of larger ensembles, including both regulatory proteins and multiple motors. Thus, single-molecule knowledge is only the start of the journey to understand cellular function and organization. The challenge is to use single-molecule information to quantitatively understand transport and its regulation in a cellular context. This article discusses this process focusing on kinesin and dynein, highlighting progress to date, and the challenges involved in using single-molecule function to understand in vivo transport." @default.
- W8004490 created "2016-06-24" @default.
- W8004490 creator A5022868249 @default.
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- W8004490 date "2012-01-01" @default.
- W8004490 modified "2023-09-23" @default.
- W8004490 title "4.15 Intracellular Transport: Relating Single-Molecule Properties to In Vivo Function" @default.
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- W8004490 doi "https://doi.org/10.1016/b978-0-12-374920-8.00418-5" @default.
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