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• W80220315 abstract "Event Abstract Back to Event Can the Pontine Reticular Formation be the (6Hz) theta generator? Péter Baracskay1*, Nora Szilagyi2, Gabor Juhasz1 and Andras Czurko1 1 Institute of Biology, Eotvos Lorand University, Hungary 2 Department of Physiology and Neurobiology, Eotvos Lorand University, Hungary Pontine Reticular Formation (PRF) as recently has been revealed are involved in the development of generalized convulsive status epilepticus (GCSE). To examine its detailed functional role in GCSE, NMDA was microinjected locally into the PnO (pontine reticular nucleus, oral part) and local field potentials (EEG) was recorded from the frontal and parietal cortex, hippocampus and contralateral PRF. Different concentration of NMDA with both pressure injection (N=4) and microosmotic pump (N=4) induced lesion (100 mmol, N=1), GCSE (10 mmol, N=3) and surprisingly sustained theta (6 Hz) activity (1 mmol, N=5) in the PRF, hippocampus and cortex. As in the current theta model (Vertes and Kocsis, 1997) the PnO only has a tonic influence on the SUM (supramammillary nucleus) where the rhythmic pattern of theta generated, we isolated the SUM from the PnO (N=3) and after the 1 mmol NMDA injection the 6 Hz theta was still revealed in the contralateral PRF. This suggests that the PRF by itself can generate the rhythmic theta pattern. Furthermore, the amplitude of the PRF theta was (>3 times) higher than the hippocampal theta and the theta phase segregation analysis demonstrated its leading role. Conference: 12th Meeting of the Hungarian Neuroscience Society, Budapest, Hungary, 22 Jan - 24 Jan, 2009. Presentation Type: Poster Presentation Topic: Developmental neurobiology and subcortical functions Citation: Baracskay P, Szilagyi N, Juhasz G and Czurko A (2009). Can the Pontine Reticular Formation be the (6Hz) theta generator?. Front. Syst. Neurosci. Conference Abstract: 12th Meeting of the Hungarian Neuroscience Society. doi: 10.3389/conf.neuro.01.2009.04.044 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Feb 2009; Published Online: 27 Feb 2009. * Correspondence: Péter Baracskay, Institute of Biology, Eotvos Lorand University, Budapest, Hungary, baracskay@freemail.hu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Péter Baracskay Nora Szilagyi Gabor Juhasz Andras Czurko Google Péter Baracskay Nora Szilagyi Gabor Juhasz Andras Czurko Google Scholar Péter Baracskay Nora Szilagyi Gabor Juhasz Andras Czurko PubMed Péter Baracskay Nora Szilagyi Gabor Juhasz Andras Czurko Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W80220315 title "Can the Pontine Reticular Formation be the (6Hz) theta generator?" @default.
• W80220315 doi "https://doi.org/10.3389/conf.neuro.01.2009.04.044" @default.
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