FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W803349917> ?p ?o ?g. }

• W803349917 endingPage "1290" @default.
• W803349917 startingPage "1283" @default.
• W803349917 abstract "Development and validation of a selective, robust high-performance liquid chromatography-tandem mass spectrometric (HPLC/MS-MS) method for the quantification of morphine, morphine-3-β-glucuronide, morphine-6-β-glucuronide, hydromorphone, and normorphine in human serum.Drug-free human serum samples spiked with morphine, morphine-3-β-glucuronide, morphine-6-β-glucuronide, hydromorphone, and normorphine were prepared by protein precipitation using methanol containing the internal standards. Samples were injected onto a Thermo Scientific AccuCore PFP column for chromatographic separation. Detection was achieved using a Thermo Scientific TSQ Vantage mass spectrometer. Assay validation followed the new Clinical and Laboratory Standards Institute (CLSI) C62-A guidelines.The analytical measuring range for all analytes was determined to be 5 to 1000 ng/mL. Intra- and inter-assay precision for three quality control levels were ≤ 7.0% and ≤ 13.5%, respectively. Carryover, stability, linearity, matrix effects, extraction and processing efficiency and method comparison characteristics were acceptable relative to the CLSI C62 guidelines.The validation of this HPLC-MS/MS method demonstrated a robust and rapid assay for the quantification of morphine, morphine-3-β-glucuronide, morphine-6-β-glucuronide, hydromorphone, and normorphine." @default.
• W803349917 created "2016-06-24" @default.
• W803349917 creator A5003392170 @default.
• W803349917 creator A5015353795 @default.
• W803349917 creator A5047143841 @default.
• W803349917 creator A5083112200 @default.
• W803349917 date "2015-12-01" @default.
• W803349917 modified "2023-10-14" @default.
• W803349917 title "The development of a high-performance liquid chromatography–tandem mass spectrometric method for simultaneous quantification of morphine, morphine-3-β-glucuronide, morphine-6-β-glucuronide, hydromorphone, and normorphine in serum" @default.
• W803349917 cites W1965307957 @default.
• W803349917 cites W2002172279 @default.
• W803349917 cites W2004320277 @default.
• W803349917 cites W2009242633 @default.
• W803349917 cites W2010365552 @default.
• W803349917 cites W2021256567 @default.
• W803349917 cites W2029445962 @default.
• W803349917 cites W2031932106 @default.
• W803349917 cites W2050226999 @default.
• W803349917 cites W2061384308 @default.
• W803349917 cites W2099863580 @default.
• W803349917 cites W2102836669 @default.
• W803349917 cites W2106389283 @default.
• W803349917 cites W2110969357 @default.
• W803349917 cites W2144682402 @default.
• W803349917 cites W2152439370 @default.
• W803349917 cites W2154634960 @default.
• W803349917 cites W2165594213 @default.
• W803349917 doi "https://doi.org/10.1016/j.clinbiochem.2015.05.023" @default.
• W803349917 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4679425" @default.
• W803349917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26118474" @default.
• W803349917 hasPublicationYear "2015" @default.
• W803349917 type Work @default.
• W803349917 sameAs 803349917 @default.
• W803349917 citedByCount "14" @default.
• W803349917 countsByYear W8033499172016 @default.
• W803349917 countsByYear W8033499172017 @default.
• W803349917 countsByYear W8033499172018 @default.
• W803349917 countsByYear W8033499172019 @default.
• W803349917 countsByYear W8033499172020 @default.
• W803349917 countsByYear W8033499172021 @default.
• W803349917 crossrefType "journal-article" @default.
• W803349917 hasAuthorship W803349917A5003392170 @default.
• W803349917 hasAuthorship W803349917A5015353795 @default.
• W803349917 hasAuthorship W803349917A5047143841 @default.
• W803349917 hasAuthorship W803349917A5083112200 @default.
• W803349917 hasBestOaLocation W8033499172 @default.
• W803349917 hasConcept C10390740 @default.
• W803349917 hasConcept C119128265 @default.
• W803349917 hasConcept C162356407 @default.
• W803349917 hasConcept C170493617 @default.
• W803349917 hasConcept C179998833 @default.
• W803349917 hasConcept C185592680 @default.
• W803349917 hasConcept C2777389121 @default.
• W803349917 hasConcept C2777477808 @default.
• W803349917 hasConcept C2779158186 @default.
• W803349917 hasConcept C2779186261 @default.
• W803349917 hasConcept C2781063702 @default.
• W803349917 hasConcept C31827203 @default.
• W803349917 hasConcept C43617362 @default.
• W803349917 hasConcept C55493867 @default.
• W803349917 hasConcept C71924100 @default.
• W803349917 hasConcept C74774607 @default.
• W803349917 hasConcept C98274493 @default.
• W803349917 hasConceptScore W803349917C10390740 @default.
• W803349917 hasConceptScore W803349917C119128265 @default.
• W803349917 hasConceptScore W803349917C162356407 @default.
• W803349917 hasConceptScore W803349917C170493617 @default.
• W803349917 hasConceptScore W803349917C179998833 @default.
• W803349917 hasConceptScore W803349917C185592680 @default.
• W803349917 hasConceptScore W803349917C2777389121 @default.
• W803349917 hasConceptScore W803349917C2777477808 @default.
• W803349917 hasConceptScore W803349917C2779158186 @default.
• W803349917 hasConceptScore W803349917C2779186261 @default.
• W803349917 hasConceptScore W803349917C2781063702 @default.
• W803349917 hasConceptScore W803349917C31827203 @default.
• W803349917 hasConceptScore W803349917C43617362 @default.
• W803349917 hasConceptScore W803349917C55493867 @default.
• W803349917 hasConceptScore W803349917C71924100 @default.
• W803349917 hasConceptScore W803349917C74774607 @default.
• W803349917 hasConceptScore W803349917C98274493 @default.
• W803349917 hasFunder F4320312526 @default.
• W803349917 hasFunder F4320332161 @default.
• W803349917 hasIssue "18" @default.
• W803349917 hasLocation W8033499171 @default.
• W803349917 hasLocation W8033499172 @default.
• W803349917 hasLocation W8033499173 @default.
• W803349917 hasLocation W8033499174 @default.
• W803349917 hasOpenAccess W803349917 @default.
• W803349917 hasPrimaryLocation W8033499171 @default.
• W803349917 hasRelatedWork W1986005472 @default.
• W803349917 hasRelatedWork W1989080374 @default.
• W803349917 hasRelatedWork W2000950530 @default.
• W803349917 hasRelatedWork W2044145238 @default.
• W803349917 hasRelatedWork W2048027784 @default.
• W803349917 hasRelatedWork W2078718962 @default.
• W803349917 hasRelatedWork W2141316828 @default.
• W803349917 hasRelatedWork W2160522961 @default.
• W803349917 hasRelatedWork W2465725187 @default.

• next