Matches in SemOpenAlex for { <https://semopenalex.org/work/W804495381> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W804495381 abstract "Spaceflight is a uniquely stressful environment with astronauts experiencing a variety of stressors including: isolation and confinement, psychosocial, noise, sleep deprivation, anxiety, variable gravitational forces, and increased radiation. These stressors are manifested through the HPA and SAM axes resulting in increased stress hormones. Diminished T-lymphocyte functions lead to reactivation of latent herpes viruses in astronauts during spaceflight. Herpes simplex virus reactivated with symptoms during spaceflight whereas Epstein-Barr virus (EBV), cytomegalovirus (CMV), and varicella zoster virus (VZV) reactivate and are shed without symptoms. EBV and VZV are shed in saliva and CMV in the urine. The levels of EBV shed in astronauts increased 10-fold during the flight; CMV and VZV are not typically shed in low stressed individuals, but both were shed in astronauts during spaceflight. All herpesviruses were detected by polymerase chain reaction (PCR) assay. Culturing revealed that VZV shed in saliva was infectious virus. The PCR technology was extended to test saliva of 54 shingles patients. All shingles patients shed VZV in their saliva, and the levels followed the course of the disease. Viremia was also found to be common during shingles. The technology may be used before zoster lesions appear allowing for prevention of disease. The technology may be used for rapid detection of VZV in doctors? offices. These studies demonstrated the value of applying technologies designed for astronauts to people on Earth." @default.
- W804495381 created "2016-06-24" @default.
- W804495381 creator A5020203646 @default.
- W804495381 creator A5034076173 @default.
- W804495381 date "2010-01-01" @default.
- W804495381 modified "2023-09-27" @default.
- W804495381 title "Salivary Varicella Zoster Virus in Astronauts and in Patients of Herpes Zoster" @default.
- W804495381 hasPublicationYear "2010" @default.
- W804495381 type Work @default.
- W804495381 sameAs 804495381 @default.
- W804495381 citedByCount "0" @default.
- W804495381 crossrefType "journal-article" @default.
- W804495381 hasAuthorship W804495381A5020203646 @default.
- W804495381 hasAuthorship W804495381A5034076173 @default.
- W804495381 hasConcept C103888896 @default.
- W804495381 hasConcept C126322002 @default.
- W804495381 hasConcept C127413603 @default.
- W804495381 hasConcept C146978453 @default.
- W804495381 hasConcept C159047783 @default.
- W804495381 hasConcept C203014093 @default.
- W804495381 hasConcept C2522874641 @default.
- W804495381 hasConcept C2776159415 @default.
- W804495381 hasConcept C2776185481 @default.
- W804495381 hasConcept C2776409557 @default.
- W804495381 hasConcept C2779001537 @default.
- W804495381 hasConcept C2780727368 @default.
- W804495381 hasConcept C2781196997 @default.
- W804495381 hasConcept C504460877 @default.
- W804495381 hasConcept C71924100 @default.
- W804495381 hasConceptScore W804495381C103888896 @default.
- W804495381 hasConceptScore W804495381C126322002 @default.
- W804495381 hasConceptScore W804495381C127413603 @default.
- W804495381 hasConceptScore W804495381C146978453 @default.
- W804495381 hasConceptScore W804495381C159047783 @default.
- W804495381 hasConceptScore W804495381C203014093 @default.
- W804495381 hasConceptScore W804495381C2522874641 @default.
- W804495381 hasConceptScore W804495381C2776159415 @default.
- W804495381 hasConceptScore W804495381C2776185481 @default.
- W804495381 hasConceptScore W804495381C2776409557 @default.
- W804495381 hasConceptScore W804495381C2779001537 @default.
- W804495381 hasConceptScore W804495381C2780727368 @default.
- W804495381 hasConceptScore W804495381C2781196997 @default.
- W804495381 hasConceptScore W804495381C504460877 @default.
- W804495381 hasConceptScore W804495381C71924100 @default.
- W804495381 hasLocation W8044953811 @default.
- W804495381 hasOpenAccess W804495381 @default.
- W804495381 hasPrimaryLocation W8044953811 @default.
- W804495381 hasRelatedWork W1479829579 @default.
- W804495381 hasRelatedWork W1938497385 @default.
- W804495381 hasRelatedWork W1972709431 @default.
- W804495381 hasRelatedWork W1992978032 @default.
- W804495381 hasRelatedWork W2031711168 @default.
- W804495381 hasRelatedWork W2092067143 @default.
- W804495381 hasRelatedWork W2145535969 @default.
- W804495381 hasRelatedWork W2158144794 @default.
- W804495381 hasRelatedWork W2558637020 @default.
- W804495381 hasRelatedWork W2905819132 @default.
- W804495381 hasRelatedWork W2914792005 @default.
- W804495381 hasRelatedWork W2947513345 @default.
- W804495381 hasRelatedWork W2954106382 @default.
- W804495381 hasRelatedWork W3082726301 @default.
- W804495381 hasRelatedWork W3088584405 @default.
- W804495381 hasRelatedWork W3199354132 @default.
- W804495381 hasRelatedWork W756929032 @default.
- W804495381 hasRelatedWork W829361289 @default.
- W804495381 hasRelatedWork W978309786 @default.
- W804495381 hasRelatedWork W2265716056 @default.
- W804495381 isParatext "false" @default.
- W804495381 isRetracted "false" @default.
- W804495381 magId "804495381" @default.
- W804495381 workType "article" @default.