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- W80706282 abstract "Sexual reproduction is fundamental to the survival and propagation of metazoan species. In mice, as in most mammals, sex is determined at the time of fertilization when a Y- or X-chromosome-bearing sperm fuses with the X-chromosome-containing egg, resulting in an XY or XX embryo. The Y chromosome contains the male-determining factor Sry, which drives the differentiation of the bipotential gonads into testes. Without Sry, the gonads develop into ovaries. Testes and ovaries then regulate the development of all other secondary sexual characteristics through the secretion of steroid hormones. In this article, we discuss the cell and molecular biology that underlies sex determination in the mouse." @default.
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- W80706282 date "2013-01-01" @default.
- W80706282 modified "2023-10-17" @default.
- W80706282 title "Sex Determination, Mouse" @default.
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- W80706282 doi "https://doi.org/10.1016/b978-0-12-374984-0.01403-0" @default.
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