Matches in SemOpenAlex for { <https://semopenalex.org/work/W80879622> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W80879622 endingPage "15" @default.
- W80879622 startingPage "11" @default.
- W80879622 abstract "Emoxypine, thiotriazoline, and NN-103 (a 4-hydrazinoquinasoline derivative) exhibit a pronounced neuroprotective action during acute cerebral stroke. Emoxypine and thiotriazoline are more effective in inhibiting death of neurons in the sensomotor area of the frontal cortex, while NN-103 is more active in the hippocampus. The ischemic death of neurons in the sensomotors area of the frontal cortex with equal probability takes place by karyopyknosis or cytolysis, while in the hippocampus, mainly by cytolysis. All preparations (except for piracetam) with antioxidants properties are powerful membranoprotective agents, which is confirmed by a considerable decrease in the rate of cytolysis both in the cortex and in the hippocampus. The use of piracetam in the case of acute cerebral stroke increases the rate of neuronal death in various areas of the cortex, up to complete destruction of nerve tissues with the formation of cysts (in hippocampus). The tested preparations exhibit different mechanism of neuroprotection: emoxypine and NN-103 (in the sensomotor area of the frontal cortex and hippocampus) and thiotriazoline (in the hippocampus) produce the neuroprotection action on the background of increased activity of transmissions and transcription processes, while thiotriazoline (in the sensomotor area of the frontal cortex) offers neuroprotection on the background of inhibited transcription and transmission activity." @default.
- W80879622 created "2016-06-24" @default.
- W80879622 creator A5000109407 @default.
- W80879622 creator A5017077656 @default.
- W80879622 creator A5037274638 @default.
- W80879622 creator A5058540988 @default.
- W80879622 creator A5064844615 @default.
- W80879622 creator A5075351136 @default.
- W80879622 date "2006-09-01" @default.
- W80879622 modified "2023-09-24" @default.
- W80879622 title "Pharmacological neuroprotection against experimental acute cerebral ischemia of neurons of sensomotor area of frontal cortex and hippocampus in rats" @default.
- W80879622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17153958" @default.
- W80879622 hasPublicationYear "2006" @default.
- W80879622 type Work @default.
- W80879622 sameAs 80879622 @default.
- W80879622 citedByCount "0" @default.
- W80879622 crossrefType "journal-article" @default.
- W80879622 hasAuthorship W80879622A5000109407 @default.
- W80879622 hasAuthorship W80879622A5017077656 @default.
- W80879622 hasAuthorship W80879622A5037274638 @default.
- W80879622 hasAuthorship W80879622A5058540988 @default.
- W80879622 hasAuthorship W80879622A5064844615 @default.
- W80879622 hasAuthorship W80879622A5075351136 @default.
- W80879622 hasConcept C169760540 @default.
- W80879622 hasConcept C185592680 @default.
- W80879622 hasConcept C25498285 @default.
- W80879622 hasConcept C2777348757 @default.
- W80879622 hasConcept C2777496795 @default.
- W80879622 hasConcept C2781041448 @default.
- W80879622 hasConcept C2781161787 @default.
- W80879622 hasConcept C71924100 @default.
- W80879622 hasConcept C86803240 @default.
- W80879622 hasConceptScore W80879622C169760540 @default.
- W80879622 hasConceptScore W80879622C185592680 @default.
- W80879622 hasConceptScore W80879622C25498285 @default.
- W80879622 hasConceptScore W80879622C2777348757 @default.
- W80879622 hasConceptScore W80879622C2777496795 @default.
- W80879622 hasConceptScore W80879622C2781041448 @default.
- W80879622 hasConceptScore W80879622C2781161787 @default.
- W80879622 hasConceptScore W80879622C71924100 @default.
- W80879622 hasConceptScore W80879622C86803240 @default.
- W80879622 hasIssue "5" @default.
- W80879622 hasLocation W808796221 @default.
- W80879622 hasLocation W808796222 @default.
- W80879622 hasOpenAccess W80879622 @default.
- W80879622 hasPrimaryLocation W808796221 @default.
- W80879622 hasRelatedWork W1726466638 @default.
- W80879622 hasRelatedWork W1973255047 @default.
- W80879622 hasRelatedWork W1974411934 @default.
- W80879622 hasRelatedWork W1979347292 @default.
- W80879622 hasRelatedWork W1992520440 @default.
- W80879622 hasRelatedWork W2008162521 @default.
- W80879622 hasRelatedWork W2036316405 @default.
- W80879622 hasRelatedWork W2086937462 @default.
- W80879622 hasRelatedWork W2347813432 @default.
- W80879622 hasRelatedWork W2403289102 @default.
- W80879622 hasRelatedWork W2409431622 @default.
- W80879622 hasRelatedWork W2414938148 @default.
- W80879622 hasRelatedWork W2620837845 @default.
- W80879622 hasRelatedWork W2753371683 @default.
- W80879622 hasRelatedWork W2791200357 @default.
- W80879622 hasRelatedWork W3035715541 @default.
- W80879622 hasRelatedWork W3127056318 @default.
- W80879622 hasRelatedWork W873570606 @default.
- W80879622 hasRelatedWork W2443903249 @default.
- W80879622 hasRelatedWork W2971440425 @default.
- W80879622 hasVolume "69" @default.
- W80879622 isParatext "false" @default.
- W80879622 isRetracted "false" @default.
- W80879622 magId "80879622" @default.
- W80879622 workType "article" @default.