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- W81114375 abstract "This chapter presents a study analyzing the effect of caffeine on mechanical activation in cut skeletal muscle fibers. The experiments were carried out at 2–4°C on single fibers dissected from the semitendinosus muscle of the frogs Rana esculenta. The fibers were cut near the tendon in relaxing solution and mounted in a two pool chamber. A single vaseline gap was used to separate the intact terminated segment from the pool containing the cut end. After completing the separation the solutions were changed to block all the ionic conductances, for Ca-containing TEA-Cs-sulfate-Ringer in the closed end pool, and for Cs-glutamate relaxing solution in the open end pool. Both the voltage difference and the total current flowing between the pools were monitored. It was found that the strength duration relation for mechanical threshold was shifted into negative direction by 0.5 mM caffeine. In case of shorter pulses the shift was more definite." @default.
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- W81114375 date "1981-01-01" @default.
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- W81114375 title "EFFECT OF CAFFEINE ON MECHANICAL ACTIVATION IN CUT SKELETAL MUSCLE FIBRES" @default.
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- W81114375 doi "https://doi.org/10.1016/b978-0-08-026817-0.50051-2" @default.
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