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• W816351696 abstract "This chapter provides an overview of visualization and analysis techniques applied to large-scale datasets from genomics, metabolomics, and proteomics. The aim is to reduce the number of variables (genes, metabolites, or proteins) by extracting a small set of new relevant variables, usually termed components. The advantages and disadvantages of the classical principal component analysis (PC A) are discussed and a link is given to the closely related singular value decomposition and multidimensional scaling. Special emphasis is given to the recent trend toward the use of independent component analysis, which aims to extract statistically independent components and, therefore, provides usually more meaningful components than PCA. We also discuss normalization techniques and their influence on the result of different analytical techniques." @default.
• W816351696 created "2016-06-24" @default.
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• W816351696 date "2007-01-01" @default.
• W816351696 modified "2023-10-18" @default.
• W816351696 title "Visualization and Analysis of Molecular Data" @default.
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• W816351696 doi "https://doi.org/10.1007/978-1-59745-244-1_6" @default.
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