Matches in SemOpenAlex for { <https://semopenalex.org/work/W8163929> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W8163929 endingPage "4" @default.
- W8163929 startingPage "60" @default.
- W8163929 abstract "A bioavailability study of rifampicin 450 mg caplets and rifampicin 600 mg caplets was carried out in 20 healthy male subjects. The higher dose was administered to subjects with a body weight greater than 50 kg. Subjects were divided into two groups where group 1 was treated with a single oral dose of 450 mg rifampicin in fasting condition. Group 2 was treated in the same way as group 1, but with a dose of 600 mg rifampicin. Our results in group 1 show peak heights of serum levels of rifampicin ranging from 13.6 to 21.0 micrograms X ml-1 (mean value was 17.6 micrograms X ml-1). AUC values ranged from 81.1 to 177.9 micrograms X ml-1h (mean value was 145.2 micrograms X ml-1 h.) Respective figures with 600 mg rifampicin were 11.0 to 27 micrograms X ml-1 (mean = 20.0 micrograms X ml-1) for peak heights and 132.0 to 260.6 micrograms X ml-1h (mean value = 181.1 micrograms X ml-1h) for AUC. In vitro dissolution tests were conducted on the same batch of respective products. Results show that maximum dissolution occurred in 15 minutes. It is concluded that our results were rather high compared to what has been reported so far. It has been suggested to reduce the dose to body weight ratio for rifampicin." @default.
- W8163929 created "2016-06-24" @default.
- W8163929 creator A5014280909 @default.
- W8163929 creator A5038807888 @default.
- W8163929 creator A5051860262 @default.
- W8163929 creator A5088710895 @default.
- W8163929 date "1986-02-01" @default.
- W8163929 modified "2023-09-27" @default.
- W8163929 title "Bioavailability of rifampicin caplets (600 mg and 450 mg) in healthy Indonesian subjects." @default.
- W8163929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3957493" @default.
- W8163929 hasPublicationYear "1986" @default.
- W8163929 type Work @default.
- W8163929 sameAs 8163929 @default.
- W8163929 citedByCount "4" @default.
- W8163929 countsByYear W81639292013 @default.
- W8163929 countsByYear W81639292014 @default.
- W8163929 countsByYear W81639292017 @default.
- W8163929 crossrefType "journal-article" @default.
- W8163929 hasAuthorship W8163929A5014280909 @default.
- W8163929 hasAuthorship W8163929A5038807888 @default.
- W8163929 hasAuthorship W8163929A5051860262 @default.
- W8163929 hasAuthorship W8163929A5088710895 @default.
- W8163929 hasConcept C105795698 @default.
- W8163929 hasConcept C126322002 @default.
- W8163929 hasConcept C140793950 @default.
- W8163929 hasConcept C147583825 @default.
- W8163929 hasConcept C181389837 @default.
- W8163929 hasConcept C185592680 @default.
- W8163929 hasConcept C2778607973 @default.
- W8163929 hasConcept C2988626262 @default.
- W8163929 hasConcept C33923547 @default.
- W8163929 hasConcept C501593827 @default.
- W8163929 hasConcept C55493867 @default.
- W8163929 hasConcept C71924100 @default.
- W8163929 hasConcept C86803240 @default.
- W8163929 hasConcept C98274493 @default.
- W8163929 hasConceptScore W8163929C105795698 @default.
- W8163929 hasConceptScore W8163929C126322002 @default.
- W8163929 hasConceptScore W8163929C140793950 @default.
- W8163929 hasConceptScore W8163929C147583825 @default.
- W8163929 hasConceptScore W8163929C181389837 @default.
- W8163929 hasConceptScore W8163929C185592680 @default.
- W8163929 hasConceptScore W8163929C2778607973 @default.
- W8163929 hasConceptScore W8163929C2988626262 @default.
- W8163929 hasConceptScore W8163929C33923547 @default.
- W8163929 hasConceptScore W8163929C501593827 @default.
- W8163929 hasConceptScore W8163929C55493867 @default.
- W8163929 hasConceptScore W8163929C71924100 @default.
- W8163929 hasConceptScore W8163929C86803240 @default.
- W8163929 hasConceptScore W8163929C98274493 @default.
- W8163929 hasIssue "2" @default.
- W8163929 hasLocation W81639291 @default.
- W8163929 hasOpenAccess W8163929 @default.
- W8163929 hasPrimaryLocation W81639291 @default.
- W8163929 hasRelatedWork W2044363921 @default.
- W8163929 hasRelatedWork W2047281641 @default.
- W8163929 hasRelatedWork W2054910784 @default.
- W8163929 hasRelatedWork W2079482958 @default.
- W8163929 hasRelatedWork W2333863647 @default.
- W8163929 hasRelatedWork W2348082371 @default.
- W8163929 hasRelatedWork W2351236749 @default.
- W8163929 hasRelatedWork W2398732098 @default.
- W8163929 hasRelatedWork W2748952813 @default.
- W8163929 hasRelatedWork W2899084033 @default.
- W8163929 hasVolume "24" @default.
- W8163929 isParatext "false" @default.
- W8163929 isRetracted "false" @default.
- W8163929 magId "8163929" @default.
- W8163929 workType "article" @default.