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- W81661503 abstract "Publisher Summary This chapter explains the evaluation of conductive Na+ current from lumen to cell across the apical membrane of the proximal tubule in Necturus. It allows a lower estimate of the active Na+ extrusion at the basolateral membrane. The conductive Na+ current at the apical membrane is equal to the driving force for passive Na+ transport across this barrier, multiplied by its partial Na+ conductance. The chapter describes the experimental design, which is used to assess the partial Na+ conductance of the luminal membrane. This task is achieved in two steps.(1) The luminal membrane resistance is quantitatively evaluated; since the resistance of single cell membranes cannot be assessed individually in epithelia, the resistances of the three barriers of the proximal tubule—luminal membrane resistance, basolateral membrane resistance, and shunt resistance, are determined. (2) The transport number of sodium is measured at the luminal membrane; it is by definition equal to the ratio of the partial Na+ conductance to the total membrane conductance. Similar measurements are performed at the basolateral membrane." @default.
- W81661503 created "2016-06-24" @default.
- W81661503 creator A5063427377 @default.
- W81661503 date "1981-01-01" @default.
- W81661503 modified "2023-10-16" @default.
- W81661503 title "ELECTRICAL PROPERTIES OF PROXIMAL TUBULAR CELL MEMBRANES OF NECTURUS KIDNEY" @default.
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- W81661503 doi "https://doi.org/10.1016/b978-0-08-026824-8.50054-0" @default.
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