Matches in SemOpenAlex for { <https://semopenalex.org/work/W817504850> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W817504850 abstract "Optical coherence tomography (OCT) is usually employed for the measurement of retinal thickness characterizing the structural changes of tissue. However, fractal dimension (FD) could also character the structural changes of tissue. Therefore, fractal dimension changes may provide further information regarding cellular layers and early damage in ocular diseases. We investigated the possibility of OCT in detecting changes in fractal dimension from layered retinal structures. OCT images were obtained from diabetic patients without retinopathy (DM, n = 38 eyes) or mild diabetic retinopathy (MDR, n = 43 eyes) and normal healthy subjects (Controls, n = 74 eyes). Fractal dimension was calculated using the differentiate box counting methodology. We evaluated the usefulness of quantifying fractal dimension of layered structures in the detection of retinal damage. Generalized estimating equations considering within-subject intereye relations were used to test for differences between the groups. A modified p value of <0.001 was considered statistically significant. Receiver operating characteristic (ROC) curves were constructed to describe the ability of fractal dimension to discriminate between the eyes of DM, MDR and healthy eyes. Significant decreases of fractal dimension were observed in all layers in the MDR eyes compared with controls except in the inner nuclear layer (INL). Significant decreases of fractal dimension were also observed in all layers in the MDR eyes compared with DM eyes. The highest area under receiver operating characteristic curve (AUROC) values estimated for fractal dimension were observed for the outer plexiform layer (OPL) and outer segment photoreceptors (OS) when comparing MDR eyes with controls. The highest AUROC value estimated for fractal dimension were also observed for the retinal nerve fiber layer (RNFL) and OS when comparing MDR eyes with DM eyes. Our results suggest that fractal dimension of the intraretinal layers may provide useful information to differentiate pathological from healthy eyes. Further research is warranted to determine how this approach may be used to improve diagnosis of early retinal neurodegeneration." @default.
- W817504850 created "2016-06-24" @default.
- W817504850 creator A5001011802 @default.
- W817504850 creator A5030603287 @default.
- W817504850 creator A5035231615 @default.
- W817504850 creator A5037078640 @default.
- W817504850 creator A5075638427 @default.
- W817504850 creator A5076994119 @default.
- W817504850 date "2015-07-09" @default.
- W817504850 modified "2023-10-16" @default.
- W817504850 title "Investigation of changes in fractal dimension from layered retinal structures of healthy and diabetic eyes with optical coherence tomography" @default.
- W817504850 cites W1975522329 @default.
- W817504850 cites W1981318504 @default.
- W817504850 cites W1987763256 @default.
- W817504850 cites W1989890904 @default.
- W817504850 cites W1999866833 @default.
- W817504850 cites W2012337697 @default.
- W817504850 cites W2080017726 @default.
- W817504850 cites W2121051633 @default.
- W817504850 cites W2146263616 @default.
- W817504850 cites W2418802570 @default.
- W817504850 doi "https://doi.org/10.1117/12.2185222" @default.
- W817504850 hasPublicationYear "2015" @default.
- W817504850 type Work @default.
- W817504850 sameAs 817504850 @default.
- W817504850 citedByCount "1" @default.
- W817504850 countsByYear W8175048502016 @default.
- W817504850 crossrefType "proceedings-article" @default.
- W817504850 hasAuthorship W817504850A5001011802 @default.
- W817504850 hasAuthorship W817504850A5030603287 @default.
- W817504850 hasAuthorship W817504850A5035231615 @default.
- W817504850 hasAuthorship W817504850A5037078640 @default.
- W817504850 hasAuthorship W817504850A5075638427 @default.
- W817504850 hasAuthorship W817504850A5076994119 @default.
- W817504850 hasBestOaLocation W8175048501 @default.
- W817504850 hasConcept C118487528 @default.
- W817504850 hasConcept C120665830 @default.
- W817504850 hasConcept C121332964 @default.
- W817504850 hasConcept C134306372 @default.
- W817504850 hasConcept C163716698 @default.
- W817504850 hasConcept C202444582 @default.
- W817504850 hasConcept C26546657 @default.
- W817504850 hasConcept C2777413408 @default.
- W817504850 hasConcept C2778818243 @default.
- W817504850 hasConcept C2780827179 @default.
- W817504850 hasConcept C2781181686 @default.
- W817504850 hasConcept C33676613 @default.
- W817504850 hasConcept C33923547 @default.
- W817504850 hasConcept C40636538 @default.
- W817504850 hasConcept C62520636 @default.
- W817504850 hasConcept C71924100 @default.
- W817504850 hasConceptScore W817504850C118487528 @default.
- W817504850 hasConceptScore W817504850C120665830 @default.
- W817504850 hasConceptScore W817504850C121332964 @default.
- W817504850 hasConceptScore W817504850C134306372 @default.
- W817504850 hasConceptScore W817504850C163716698 @default.
- W817504850 hasConceptScore W817504850C202444582 @default.
- W817504850 hasConceptScore W817504850C26546657 @default.
- W817504850 hasConceptScore W817504850C2777413408 @default.
- W817504850 hasConceptScore W817504850C2778818243 @default.
- W817504850 hasConceptScore W817504850C2780827179 @default.
- W817504850 hasConceptScore W817504850C2781181686 @default.
- W817504850 hasConceptScore W817504850C33676613 @default.
- W817504850 hasConceptScore W817504850C33923547 @default.
- W817504850 hasConceptScore W817504850C40636538 @default.
- W817504850 hasConceptScore W817504850C62520636 @default.
- W817504850 hasConceptScore W817504850C71924100 @default.
- W817504850 hasLocation W8175048501 @default.
- W817504850 hasOpenAccess W817504850 @default.
- W817504850 hasPrimaryLocation W8175048501 @default.
- W817504850 hasRelatedWork W1497144211 @default.
- W817504850 hasRelatedWork W1991295273 @default.
- W817504850 hasRelatedWork W2053621563 @default.
- W817504850 hasRelatedWork W2058718475 @default.
- W817504850 hasRelatedWork W2069317917 @default.
- W817504850 hasRelatedWork W2081769848 @default.
- W817504850 hasRelatedWork W2350089091 @default.
- W817504850 hasRelatedWork W2389397070 @default.
- W817504850 hasRelatedWork W4241721205 @default.
- W817504850 hasRelatedWork W4320811032 @default.
- W817504850 isParatext "false" @default.
- W817504850 isRetracted "false" @default.
- W817504850 magId "817504850" @default.
- W817504850 workType "article" @default.