FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W81776302> ?p ?o ?g. }

• W81776302 endingPage "179" @default.
• W81776302 startingPage "175" @default.
• W81776302 abstract "Complex regional pain syndrome (CRPS) is characterized by pain that is out of proportion to the injury and is regional in distribution. A large body of literature supports a dynamic change in the physiology and structure of central pain projecting neurons mediated through the N-methyl-D-aspartate (NMDA) receptor. A critical factor in central sensitization seems to be the release of the magnesium block on the NMDA receptor with influx of calcium and initiation of intracellular cascades. Current literature supports the effectiveness of ketamine in blocking central sensitization through its effects on the NMDA receptor. Recent treatment with anesthetic doses of ketamine in severely ill patients with generalized CRPS prompted our interest in a lower dose therapy.To report on the efficacy of low dose outpatient ketamine infusion for the treatment of CRPS diagnosed by International Association for the Study of Pain (IASP) criteria in patients who have failed conservative treatment.Open label, prospective, pain journal evaluation of a 10-day infusion of intravenous ketamine in the CRPS patient.Patients diagnosed with CRPS by a single neurologist were assigned to receive a 10-day outpatient infusion of ketamine supervised by an Anesthesiologist/Pain Management Specialist. The infusion was administered in a short procedure unit after each patient had been instructed on how to complete a pain questionnaire. Monitoring consisted of continuous ECG, pulse oximetry, and non-invasive blood pressure every 15 minutes. Patients made journal entries each day prior to the infusion of 40-80 mg of ketamine. The subjects were also asked to rate their pain intensity using a verbal analog pain scale of 0-10 and the affective component using a verbal scale of 0-4.There was a significant reduction in pain intensity from initiation of infusion (Day 1) to the 10th day, with a significant reduction in the percentage of patients experiencing pain by Day 10 as well as a reduction in the level of their worst pain. The nadirs of pain were lower by Day 10 with a significant reduction in the incidence of punishing pain. Moreover, there was a significant improvement in the ability to initiate movement by the 10th day.A four-hour ketamine infusion escalated from 40-80 mg over a 10-day period can result in a significant reduction of pain with increased mobility and a tendency to decreased autonomic dysregulation." @default.
• W81776302 created "2016-06-24" @default.
• W81776302 creator A5009938422 @default.
• W81776302 creator A5017451967 @default.
• W81776302 creator A5026655418 @default.
• W81776302 creator A5037827678 @default.
• W81776302 creator A5046975019 @default.
• W81776302 creator A5055521506 @default.
• W81776302 creator A5083255476 @default.
• W81776302 creator A5084049484 @default.
• W81776302 date "2005-04-14" @default.
• W81776302 modified "2023-10-10" @default.
• W81776302 title "Multi-Day Low Dose Ketamine Infusion for the Treatment of Complex Regional Pain Syndrome" @default.
• W81776302 cites W18184263 @default.
• W81776302 cites W1984643866 @default.
• W81776302 cites W1989982590 @default.
• W81776302 cites W1990188497 @default.
• W81776302 cites W1993101304 @default.
• W81776302 cites W2000779549 @default.
• W81776302 cites W2003646312 @default.
• W81776302 cites W2016425872 @default.
• W81776302 cites W2031767814 @default.
• W81776302 cites W2032836087 @default.
• W81776302 cites W2042391150 @default.
• W81776302 cites W2042549514 @default.
• W81776302 cites W2055183272 @default.
• W81776302 cites W2114024201 @default.
• W81776302 cites W2121463325 @default.
• W81776302 cites W2145977703 @default.
• W81776302 cites W2329340405 @default.
• W81776302 doi "https://doi.org/10.36076/ppj.2005/8/175" @default.
• W81776302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16850072" @default.
• W81776302 hasPublicationYear "2005" @default.
• W81776302 type Work @default.
• W81776302 sameAs 81776302 @default.
• W81776302 citedByCount "92" @default.
• W81776302 countsByYear W817763022012 @default.
• W81776302 countsByYear W817763022013 @default.
• W81776302 countsByYear W817763022014 @default.
• W81776302 countsByYear W817763022015 @default.
• W81776302 countsByYear W817763022016 @default.
• W81776302 countsByYear W817763022017 @default.
• W81776302 countsByYear W817763022018 @default.
• W81776302 countsByYear W817763022019 @default.
• W81776302 countsByYear W817763022020 @default.
• W81776302 countsByYear W817763022021 @default.
• W81776302 countsByYear W817763022022 @default.
• W81776302 crossrefType "journal-article" @default.
• W81776302 hasAuthorship W81776302A5009938422 @default.
• W81776302 hasAuthorship W81776302A5017451967 @default.
• W81776302 hasAuthorship W81776302A5026655418 @default.
• W81776302 hasAuthorship W81776302A5037827678 @default.
• W81776302 hasAuthorship W81776302A5046975019 @default.
• W81776302 hasAuthorship W81776302A5055521506 @default.
• W81776302 hasAuthorship W81776302A5083255476 @default.
• W81776302 hasAuthorship W81776302A5084049484 @default.
• W81776302 hasBestOaLocation W817763021 @default.
• W81776302 hasConcept C126322002 @default.
• W81776302 hasConcept C170493617 @default.
• W81776302 hasConcept C2780226346 @default.
• W81776302 hasConcept C2780795376 @default.
• W81776302 hasConcept C42219234 @default.
• W81776302 hasConcept C67018056 @default.
• W81776302 hasConcept C71924100 @default.
• W81776302 hasConceptScore W81776302C126322002 @default.
• W81776302 hasConceptScore W81776302C170493617 @default.
• W81776302 hasConceptScore W81776302C2780226346 @default.
• W81776302 hasConceptScore W81776302C2780795376 @default.
• W81776302 hasConceptScore W81776302C42219234 @default.
• W81776302 hasConceptScore W81776302C67018056 @default.
• W81776302 hasConceptScore W81776302C71924100 @default.
• W81776302 hasIssue "4;2" @default.
• W81776302 hasLocation W817763021 @default.
• W81776302 hasLocation W817763022 @default.
• W81776302 hasOpenAccess W81776302 @default.
• W81776302 hasPrimaryLocation W817763021 @default.
• W81776302 hasRelatedWork W2020080842 @default.
• W81776302 hasRelatedWork W2033257871 @default.
• W81776302 hasRelatedWork W2093334854 @default.
• W81776302 hasRelatedWork W2350032813 @default.
• W81776302 hasRelatedWork W2389728407 @default.
• W81776302 hasRelatedWork W2479939550 @default.
• W81776302 hasRelatedWork W3148606814 @default.
• W81776302 hasRelatedWork W3160912258 @default.
• W81776302 hasRelatedWork W4312286332 @default.
• W81776302 hasRelatedWork W4365511141 @default.
• W81776302 hasVolume "2;8" @default.
• W81776302 isParatext "false" @default.
• W81776302 isRetracted "false" @default.
• W81776302 magId "81776302" @default.
• W81776302 workType "article" @default.