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- W81877706 abstract "A 2-year-old girl affected with the late infantile form of metachromatic leukodystrophy had a persistent and moderate metabolic acidosis. Renal functional studies demonstrated the presence of decreased tubular reabsorption of sodium, bicarbonate and some amino acids. Other tubular functions, including distal urinary acidification and concentrating mechanism were normal. Glomerular filtration rate was moderately decreased. Metachromatic inclusions were demonstrated along the nephron by histochemistry and electron microscopy. Tubular dysfunction in metachromatic leukodystrophy could have been overlooked until now given the severity of the neurological picture." @default.
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- W81877706 date "1978-04-01" @default.
- W81877706 modified "2023-09-26" @default.
- W81877706 title "Proximal renal tubular acidosis in metachromatic leukodystrophy." @default.
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