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- W81991926 abstract "1772 Objectives To evaluate the role of 18F-FDG PET/CT in initial lymph node staging including prediction of capsular invasion (CI) of oropharynx, hypopharynx and oral cavity cancer patients. Methods PET/CT images performed for initial staging in oropharyx, hypopharynx and oral cavity cancer patients from November 2003 to November 2008 were retrospectively reviewed. Patients with squamous cell carcinoma type were included. PET/CT images were interpreted by visual analysis. The maximum standardized uptake value (SUVmax) of primary tumor and metastatic LNs were recorded and correlated with histologic result by operation, location; size of the primary tumor; level of metastatic LNs; presence of CI in metastatic LNs; and immunohistochemical results. Results Sixty-one cases were included (51 male, 10 female; mean age 60±10 y). In post-operative histologic results, there was LN metastasis in 36 out of 61 patients. The sensitivity of PET/CT was 72.2%, specificity was 92.0%. The SUVmax (10.0±3.3 vs. 7.3±4.1, p=0.016) and the size of primary tumor (3.9±1.7 vs. 2.1±1.4, p Conclusions PET/CT for initial LN staging of oropharynx, hypopharynx and oral cavity cancer showed higher specificity. The presence of CI was correlated with SUVmax of primary tumor and metastatic LNs, and size of LNs." @default.
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- W81991926 date "2009-05-01" @default.
- W81991926 modified "2023-09-27" @default.
- W81991926 title "18F-FDG PET/CT in lymph node staging of oropharynx, hypopharynx and oral cavity cancer patients: Correlation with histology results" @default.
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