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- W82022846 abstract "Publisher Summary This chapter presents a study on the oxygen supply and liver metabolism in embryonic chicks. Experiments that were conducted, as a part of the study, revealed an extremely high β-hydroxybutyrateacetoacetate ratio in embryonic chick liver that reflects the redox ratio of intramitochondrial NADH and NAD+. Embryonic chick liver was unable to oxidize reducing equivalents produced at this developmental stage mainly via lipolysis. Enzymatic studies in liver mitochondria showed about tenfold higher activities of NADH oxidase compared with cytochrome c oxidase. In addition, NADH oxidation was increased by exogenous cytochrome c. On the basis of these data, it seems possible that oxidation of NADH reducing equivalents is limited by processes of the respiratory chain. l -thyroxine (T4) induced the activity of cytochrome c oxidase.. The thyroid hormone injected on day 17 of incubation into eggs caused a premature pipping of the egg shell and a premature active breathing as automatically registered by pressure changes in the air cell caused by lung respiration. Significantly, increased cytochrome c oxidase activities were observed in T4-treated embryos. However, an increased rather than a decreased β-hydroxybutyrate-acetoacetate ratio was found after the injection of T4." @default.
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- W82022846 date "1982-01-01" @default.
- W82022846 modified "2023-09-26" @default.
- W82022846 title "OXYGEN SUPPLY AND LIVER METABOLISM IN EMBRYONIC CHICKS" @default.
- W82022846 doi "https://doi.org/10.1016/b978-0-08-028845-1.50037-8" @default.
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