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- W82104119 abstract "ABSTRACT Beta-adrenergic receptors have been measured in myocardial membranes from hypertensive rats using direct binding methods with 125 I-iodohydroxybenzylpindolol. Membranes from hypertensive animals contained a lower concentration of β-receptors than control membranes. This decrease was from 110 to 75 fmol/mg protein for renal artery clip rats and from 110 to 49 fmol/mg for DOCA-salt rats. Isoproterenol stimulated adenylate cyclase activity was also lower in membranes from hypertensive animals but basal and fluoride stimulated activities were unchanged. These results suggest that there may be increased cardiac sympathetic drive in these hypertensive models." @default.
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- W82104119 date "1979-01-01" @default.
- W82104119 modified "2023-09-23" @default.
- W82104119 title "DECREASED CARDIAC BETA-ADRENERGIC RECEPTORS IN HYPERTENSIVE RATS" @default.
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- W82104119 doi "https://doi.org/10.1016/b978-1-4832-8363-0.50447-x" @default.
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